Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16088827 | 0.88 | HTT (0.61) | TRPM4HTTCCR2SMN1; SMN2KMT2A | |
| SCHEMBL23864691 | 0.76 | ALDH1A1 (0.47) | HTTMAPTGAAKDM4ENPC1 | |
| SCHEMBL16088601 | 0.76 | KMT2A (0.51) | HTTSMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL11568751 | 0.76 | GPR35 (0.69) | TRPM4HTTSMN1; SMN2KMT2AMAPT | |
| SCHEMBL29758005 | 0.76 | GPR35 (0.69) | TRPM4HTTSMN1; SMN2KMT2AMAPT | |
| SCHEMBL23864300 | 0.74 | KMT2A (0.47) | TRPM4HTTSMN1; SMN2KMT2AMAPT | |
| SCHEMBL13170059 | 0.74 | ALDH1A1 (0.54) | HTTSMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL2225438 | 0.73 | ALDH1A1 (0.57) | TRPM4HTTSMN1; SMN2MAPTKDM4E | |
| SCHEMBL16088612 | 0.72 | HTT (0.61) | HTTSMN1; SMN2KMT2AMAPTGAA | |
| SCHEMBL23486868 | 0.72 | PDK1 (0.46) | TRPM4HTTSMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |