Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP7 | O15540 | 3/20 | 0.54 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2386510 | 1.00 | FABP7 (0.54) | FABP7FABP5ALDH1A1TDP1HCAR2 | |
| SCHEMBL6816419 | 1.00 | FABP7 (0.54) | FABP7FABP5ALDH1A1TDP1HCAR2 | |
| SCHEMBL2386506 | 1.00 | FABP7 (0.54) | FABP7FABP5ALDH1A1TDP1HCAR2 | |
| Hydrochloric Acid SCHEMBL11207488 | 0.98 | FABP7 (0.53) | FABP7FABP5ALDH1A1TDP1HCAR2 | |
| SCHEMBL11652159 | 0.85 | ALDH1A1 (0.43) | FABP7FABP5ALDH1A1L3MBTL1KMT2A | |
| Potassium Ion SCHEMBL11173137 | 0.85 | FABP7 (0.47) | FABP7FABP5ALDH1A1TDP1HCAR2 | |
| SCHEMBL6069978 | 0.83 | HCAR2 (0.51) | ALDH1A1TDP1HCAR2MAPK1L3MBTL1 | |
| SCHEMBL11174768 | 0.83 | ALDH1A1 (0.47) | FABP7FABP5ALDH1A1TDP1MAPK1 | |
| SCHEMBL16488184 | 0.83 | ALDH1A1 (0.55) | FABP7FABP5ALDH1A1TDP1HCAR2 | |
| SCHEMBL15325120 | 0.83 | ALDH1A1 (0.55) | FABP7FABP5ALDH1A1TDP1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013014-B2 | Aza-peptide epoxides | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-09-06 | — | — | US | disclosed |
| US-20060172952-A1 | Aza-peptide epoxides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-08-03 | — | — | US | disclosed |
| US-7056947-B2 | For inhibiting (cysteine) proteases/caspases; for treatment of viral infections, stroke, neurodegenerative disease, and inflammatory diseases | GEORGIA TECH RESEARCH CORP. (US) | 2006-06-06 | — | — | US | disclosed |
| US-20040048327-A1 | Aza-peptide epoxides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-03-11 | — | — | US | disclosed |
| WO-2004005270-A1 | AZA-PEPTIDE EPOXIDES | GEORGIA TECH RESEARCH CORPORATION (US) | 2004-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060172952-A1 | Aza-peptide epoxides | CAPN9, CAPNS1, IAPP | FABP7 236/4885FABP5 2147/4885ALDH1A1 2999/4885 |
| US-20040048327-A1 | Aza-peptide epoxides | ANPEP, ENPEP, TMPRSS15 | FABP7 848/4885FABP5 2944/4885ALDH1A1 1762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.