Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 4/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12107918 | 0.87 | CNR1 (0.41) | ARIDO1S1PR1PTPN1 | |
| SCHEMBL12114208 | 0.86 | S1PR1 (0.37) | ARIDO1S1PR1PTPN1 | |
| SCHEMBL23865022 | 0.84 | S1PR1 (0.35) | LOXL2MAOBLOXIDO1S1PR1 | |
| SCHEMBL3898701 | 0.83 | S1PR1 (0.36) | ARIDO1S1PR1PTPN1NR1H2 | |
| SCHEMBL3908063 | 0.83 | KIF11 (0.42) | ARIDO1S1PR1 | |
| SCHEMBL19430863 | 0.82 | S1PR1 (0.36) | LOXL2MAOBLOXIDO1S1PR1 | |
| SCHEMBL23865172 | 0.80 | PTPN7 (0.45) | MAOBS1PR1CSNK2A1 | |
| SCHEMBL23865129 | 0.80 | TAAR1 (0.53) | MAOBIDO1TAAR1 | |
| SCHEMBL4550353 | 0.79 | LOXL2 (0.41) | LOXL2MAOBLOXIDO1TAAR1 | |
| SCHEMBL11802082 | 0.79 | NR1H2 (0.53) | ARIDO1S1PR1PTPN1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436451-B1 | SPHINGOSINE KINASE INHIBITOR AMIDOXIME PRODRUGS | UNIV VIRGINIA PATENT FOUNDATION (US) | 2021-09-29 | — | — | EP | disclosed |