Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | LOX | P28300 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 4/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | KLK1 | P06870 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23865166 | 0.79 | LOXL2 (0.39) | LOXL2MAOBLOXIDO1NSD2 | |
| SCHEMBL8690013 | 0.78 | LOXL2 (0.47) | LOXL2MAOBLOXIDO1NSD2 | |
| SCHEMBL23865129 | 0.76 | TAAR1 (0.53) | MAOBIDO1TAAR1 | |
| SCHEMBL15047124 | 0.76 | HRH3 (0.40) | LOXL2LOXTAAR1HRH3 | |
| SCHEMBL15692019 | 0.75 | LOXL2 (0.44) | LOXL2MAOBLOXIDO1NSD2 | |
| SCHEMBL17864251 | 0.75 | DAO (0.46) | IDO1RXRARXRBRXRG | |
| SCHEMBL17864241 | 0.75 | IDO1 (0.59) | IDO1 | |
| SCHEMBL41769 | 0.75 | PTPN7 (0.45) | LOXL2MAOBLOXIDO1TAAR1 | |
| SCHEMBL15833862 | 0.74 | IDO1 (0.35) | MAOBIDO1RXRARXRBRXRG | |
| SCHEMBL17503913 | 0.74 | KLKB1 (0.37) | LOXL2MAOBLOXIDO1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053186-A1 | ARYLAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-04-26 | — | — | WO | disclosed |