Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | PTGIR | P43119 | 2/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10264290 | 1.00 | DRD2 (0.40) | DRD2DRD4CHRM2CHRM4CHRM1 | |
| SCHEMBL6101026 | 0.86 | CHRM2 (0.41) | DRD2DRD4CHRM2CHRM4CHRM1 | |
| SCHEMBL6102422 | 0.86 | CHRM2 (0.41) | DRD2DRD4CHRM2CHRM4CHRM1 | |
| SCHEMBL11395137 | 0.86 | CHRM2 (0.41) | DRD2DRD4CHRM2CHRM4CHRM1 | |
| SCHEMBL11387073 | 0.86 | CHRM2 (0.38) | CHRM2CHRM4CHRM1CHRM3MTNR1A | |
| SCHEMBL11393893 | 0.86 | CHRM2 (0.38) | DRD2DRD4CHRM2CHRM4CHRM1 | |
| SCHEMBL12060494 | 0.83 | MTNR1A (0.40) | MTNR1AMTNR1B | |
| SCHEMBL14367870 | 0.83 | ALDH1A1 (0.41) | CHRM2CHRM4CHRM1CHRM3MTNR1A | |
| SCHEMBL14367883 | 0.83 | ALDH1A1 (0.41) | CHRM2CHRM4CHRM1CHRM3MTNR1A | |
| SCHEMBL27883632 | 0.83 | MTNR1A (0.51) | DRD2DRD4MTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3885344-A2 | PYRIMIDINE COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USES THEREOF | InventisBio Co., Ltd. (CN) | 2021-09-29 | — | — | EP | disclosed |