SCHEMBL3265662

SCHEMBL3265662

CCC(=O)NCCSSCC[C]=O

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
STAT3 P40763 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MTNR1A P48039 2/20 0.33
MTNR1B P49286 2/20 0.33
RECQL P46063 1/20 0.33
TSHR P16473 2/20 0.32
MCL1 Q07820 1/20 0.32
LMNA P02545 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
ACACB O00763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17546684 0.86 MEN1 (0.61) MEN1KMT2ASTAT3HSD17B10MTNR1A
SCHEMBL16556482 0.80 MEN1 (0.54) MEN1KMT2ASTAT3HSD17B10MTNR1A
SCHEMBL2386783 0.80
SCHEMBL17344727 0.79 MEN1 (0.64) MEN1KMT2ASTAT3HSD17B10MTNR1A
SCHEMBL25970361 0.79 TSHR (0.56) MEN1KMT2ASTAT3HSD17B10MTNR1A
Propanol SCHEMBL28627241 0.79 MEN1 (0.52) MEN1KMT2ASTAT3HSD17B10MTNR1A
SCHEMBL27512309 0.77 MEN1 (0.50) MEN1KMT2ASTAT3HSD17B10MTNR1A
SCHEMBL20224856 0.76 MEN1 (0.54) MEN1KMT2ASTAT3HSD17B10MTNR1A
SCHEMBL23419140 0.74 MEN1 (0.47) MEN1KMT2ASTAT3HSD17B10MTNR1A
SCHEMBL13367647 0.74 MEN1 (0.47) MEN1KMT2ASTAT3HSD17B10MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2673000-A2 POLYMER-CARBOHYDRATE-LIPID CONJUGATES Wu, Nian (US) 2013-12-18 EP claimed
WO-2012109112-A2 POLYMER-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2012-08-16 WO claimed
WO-2012109052-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2012-08-16 WO claimed
US-20120202979-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES LIPOSEUTICALS, INC. 2012-08-09 US claimed
US-20120202890-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2012-08-09 US claimed
US-20100076209-A1 PEG-lipid conjugates for liposomes and drug delivery BIOZONE LABORATORIES INC. 2010-03-25 US claimed
EP-3313857-B1 POLYMER-CYCLODEXTRIN-LIPID CONJUGATES WU NIAN (US) 2021-01-06 EP disclosed
US-10835608-B2 Polymer-carbohydrate conjugates for drug delivery technology LIPOSEUTICALS INC 2020-11-17 US disclosed
EP-3077006-B1 POLYMER-CARBOHYDRATE CONJUGATES FOR DRUG DELIVERY TECHNOLOGY WU NIAN (US) 2020-08-19 EP disclosed
US-10064954-B2 Polymer-cyclodextrin-lipid conjugates LIPOSEUTICALS INC 2018-09-04 US disclosed
EP-2673000-B1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2018-05-16 EP disclosed
EP-3313857-A1 POLYMER-CYCLODEXTRIN-LIPID CONJUGATES Wu, Nian (US) 2018-05-02 EP disclosed
WO-2016209732-A1 POLYMER-CYCLODEXTRIN-LIPID CONJUGATES WU NIAN (US) 2016-12-29 WO disclosed
EP-2673000-A2 POLYMER-CARBOHYDRATE-LIPID CONJUGATES Wu, Nian (US) 2013-12-18 EP disclosed
US-8304565-B2 PEG-lipid conjugates for liposomes and drug delivery BIOZONE LABORATORIES INC. 2012-11-06 US disclosed
WO-2012109112-A2 POLYMER-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2012-08-16 WO disclosed
WO-2012109052-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2012-08-16 WO disclosed
US-20120202979-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES LIPOSEUTICALS, INC. 2012-08-09 US disclosed
US-20120202890-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2012-08-09 US disclosed
US-20100076209-A1 PEG-lipid conjugates for liposomes and drug delivery BIOZONE LABORATORIES INC. 2010-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100076209-A1 PEG-lipid conjugates for liposomes and drug delivery DAGLA, DAGLB, DGKG MEN1 2105/4885KMT2A 4305/4885STAT3 4135/4885
US-10835608-B2 Polymer-carbohydrate conjugates for drug delivery technology LIPC, FABP4, CETP MEN1 2733/4885KMT2A 1977/4885STAT3 3177/4885
US-10064954-B2 Polymer-cyclodextrin-lipid conjugates CETP, FABP4, PLIN3 MEN1 3960/4885KMT2A 4200/4885STAT3 3683/4885
US-20120202890-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES LIPC, FUT6, UGCG MEN1 1849/4885KMT2A 1692/4885STAT3 4808/4885
US-20120202979-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES LIPC, FUT6, UGCG MEN1 1849/4885KMT2A 1692/4885STAT3 4808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.