Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | KDM5A | P29375 | 2/20 | 0.45 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.45 |
| ▸ | JMJD1C | Q15652 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | KDM5C | P41229 | 2/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | TET3 | O43151 | 1/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.42 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.42 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1505808 | 0.85 | KDM4E (0.57) | KDM4EKDM5AKDM3AJMJD1CALDH1A1 | |
| SCHEMBL1578942 | 0.77 | KDM4E (0.53) | KDM4EKDM5AKDM3AJMJD1CALDH1A1 | |
| SCHEMBL34461785 | 0.76 | XDH (0.56) | KDM4EKDM5AKDM3AJMJD1CALDH1A1 | |
| SCHEMBL27801110 | 0.76 | KDM4E (0.52) | KDM4EKDM5AKDM3AJMJD1CALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27766041 | 0.76 | KDM4E (0.52) | KDM4EKDM5AKDM3AJMJD1CALDH1A1 | |
| SCHEMBL27700143 | 0.73 | XDH (0.50) | KDM4EKDM5AKDM3AJMJD1CALDH1A1 | |
| SCHEMBL696116 | 0.73 | XDH (0.50) | KDM4EKDM5AKDM3AJMJD1CALDH1A1 | |
| SCHEMBL27680966 | 0.72 | XDH (0.46) | KDM4EKDM5AKDM3AJMJD1CALDH1A1 | |
| Hydrochloric Acid SCHEMBL7968706 | 0.71 | XDH (0.49) | KDM4EKDM5AKDM3AJMJD1CALDH1A1 | |
| SCHEMBL6325352 | 0.71 | KDM4E (0.55) | KDM4EKDM5AKDM3AJMJD1CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3788032-B1 | COMPOUNDS COMPRISING A LINKER FOR INCREASING TRANSCYCLOOCTENE STABILITY | TAGWORKS PHARMACEUTICALS B V (NL) | 2024-01-24 | — | — | EP | disclosed |
| US-20210308207-A1 | COMPOUNDS COMPRISING A LINKER FOR INCREASING TRANSCYCLOOCTENE STABILITY | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2021-10-07 | — | — | US | disclosed |
| US-20210299286-A1 | TETRAZINES FOR HIGH CLICK CONJUGATION YIELD IN VIVO AND HIGH CLICK RELEASE YIELD | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210299286-A1 | TETRAZINES FOR HIGH CLICK CONJUGATION YIELD IN VIVO AND HIGH CLICK RELEASE YIELD | FCER2, SQLE, TTL | KDM4E 3967/4885KDM5A 2351/4885KDM3A 4076/4885 |
| US-20210308207-A1 | COMPOUNDS COMPRISING A LINKER FOR INCREASING TRANSCYCLOOCTENE STABILITY | VIP, PIN1, QPCT | KDM4E 4319/4885KDM5A 4345/4885KDM3A 4497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.