Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.64 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.64 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.64 |
| ▸ | KDM1A | O60341 | 9/20 | 0.63 |
| ▸ | MAOA | P21397 | 7/20 | 0.63 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.63 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | CTSL | P07711 | 4/20 | 0.61 |
| ▸ | CTSB | P07858 | 2/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6801630 | 0.89 | CTSL (0.66) | CTSLCTSB | |
| SCHEMBL6801635 | 0.89 | CTSL (0.66) | CTSLCTSB | |
| SCHEMBL8205341 | 0.88 | SIRT5 (0.57) | F2PRSS1PRSS2PRSS3KDM1A | |
| SCHEMBL7370634 | 0.87 | HDAC8 (0.73) | F2PRSS1PRSS2PRSS3KDM1A | |
| SCHEMBL5348200 | 0.86 | HDAC3 (0.59) | F2PRSS1PRSS2PRSS3KDM1A | |
| SCHEMBL951558 | 0.86 | CTSL (0.65) | CTSLCTSB | |
| SCHEMBL8433969 | 0.86 | CTSL (0.62) | CTSLCTSB | |
| SCHEMBL11138908 | 0.86 | CTSL (0.65) | CTSLCTSB | |
| SCHEMBL11144067 | 0.86 | CTSL (0.65) | CTSLCTSB | |
| SCHEMBL8436808 | 0.86 | CTSL (0.62) | CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080631-A2 | CHEMO-ENZYMATIC SYNTHESIS OF A C-TERMINAL ARYL AMIDE OF AN AMINO ACID OR PEPTIDE | DSM IP ASSETS BV (NL) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009080631-A2 | CHEMO-ENZYMATIC SYNTHESIS OF A C-TERMINAL ARYL AMIDE OF AN AMINO ACID OR PEPTIDE | DSM IP ASSETS BV (NL) | 2009-07-02 | — | — | WO | disclosed |
| EP-0464388-A1 | Detection assays having chromogenic and nonchromogenic, hypocromogenic, bathochromogenic or hypsochromogenic substrates | TECHNICON INSTRUMENTS CORPORATION (a New York corporation) (US) | 1992-01-08 | — | — | EP | disclosed |
| US-RE29369-E | AMIDE PRODUCT, SALTS OF HYDROXY-SUBSTITUTED PYRIDINE COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JA) | 1977-08-23 | — | — | US | disclosed |
| US-4043992-A | Method for preparing acylated products | KYOWA HAKKO KOGYO CO., LTD. (JA) | 1977-08-23 | — | — | US | disclosed |
| US-3963728-A | ACYLATION OF NITROGEN CONTAINING COMPOUNDS USING ESTERS | KYOWA HAKKO KOGYO CO., LTD. (JA) | 1976-06-15 | — | — | US | disclosed |