Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2298335 | 0.74 | HTR2C (0.61) | EPHX1HTR2CSCN10ANISCHCTSL | |
| Hydrochloric Acid SCHEMBL4893644 | 0.73 | HTR2C (0.62) | EPHX1HTR2CSCN10AKDM1ARCOR1 | |
| SCHEMBL25307338 | 0.72 | HTR3A (0.54) | EPHX1HTR2CSCN10A | |
| SCHEMBL1247076 | 0.71 | SLC6A4 (0.39) | EPHX1HTR2CGRIN2BSLC6A4 | |
| SCHEMBL22944159 | 0.71 | SCN10A (0.61) | HTR2CSCN10A | |
| SCHEMBL19580559 | 0.69 | HTR2C (0.48) | EPHX1HTR2CSCN10ANISCHKDM1A | |
| SCHEMBL3121912 | 0.69 | HTR2C (0.45) | EPHX1HTR2CSCN10ANISCHKDM1A | |
| SCHEMBL1673897 | 0.68 | HRH1 (0.59) | EPHX1HTR2C | |
| SCHEMBL4564168 | 0.68 | L3MBTL1 (0.47) | EPHX1HTR2CNISCHKDM1ARCOR1 | |
| SCHEMBL20588412 | 0.68 | SSTR1 (0.44) | EPHX1HTR2CSCN10AKDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021191384-A1 | ARYL PIPERIDINES AS MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2021-09-30 | — | — | WO | disclosed |