SCHEMBL23874652

SCHEMBL23874652

c1ccc(-c2nc3ccccc3nc2-n2c3ccc4sc5cccc6c7cccc8c7c7c(c3c4c56)c2ccc7n8-c2ccccc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.34
CASP1 P29466 1/20 0.34
HRH4 Q9H3N8 1/20 0.34
GSR P00390 1/20 0.34
KDM4E B2RXH2 6/20 0.33
ALDH1A1 P00352 4/20 0.33
HPGD P15428 2/20 0.33
GAA P10253 1/20 0.33
PDE1B Q01064 1/20 0.33
PDE3A Q14432 1/20 0.33
PDE11A Q9HCR9 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
ATM Q13315 1/20 0.33
JUN P05412 1/20 0.32
LMNA P02545 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
POLB P06746 1/20 0.32
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23874687 0.95 HSD17B10 (0.36) HSD17B10CASP1HRH4GSRKDM4E
SCHEMBL23874823 0.91 HSD17B10 (0.36) HSD17B10CASP1HRH4KDM4EALDH1A1
SCHEMBL23874649 0.89 HSD17B10 (0.40) HSD17B10CASP1HRH4GSRKDM4E
SCHEMBL23874653 0.89 GSR (0.32) HSD17B10GSRKDM4EHPGDPDE1B
SCHEMBL23874655 0.88 MEN1 (0.31) L3MBTL1LMNAMEN1KMT2AMAPK1
SCHEMBL23874675 0.88 HSD17B10 (0.43) HSD17B10CASP1HRH4GSRKDM4E
SCHEMBL21281953 0.87 HSD17B10 (0.37) HSD17B10CASP1HRH4KDM4EALDH1A1
SCHEMBL23874647 0.87 HSD17B10 (0.39) HSD17B10CASP1HRH4GSRKDM4E
SCHEMBL24703121 0.85 ALDH1A1 (0.41) KDM4EALDH1A1HPGDGAAPDE1B
SCHEMBL23874922 0.84 ESR1 (0.38) HSD17B10CASP1HRH4GSRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220356193-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-11-10 US disclosed
US-20220173330-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-06-02 US disclosed
US-20210320263-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-14 US disclosed
US-20210305519-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220356193-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME PIEZO1, SOD1, NECTIN4 HSD17B10 4122/4885CASP1 1034/4885HRH4 4561/4885
US-20220173330-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME LEF1, ODC1, OR10J3 HSD17B10 1606/4885CASP1 368/4885HRH4 4660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.