SCHEMBL23875010

SCHEMBL23875010

c1ccc(-c2nc(-c3ccccc3)nc(-n3c4cccc5c6ccccc6c6cccc7oc8ccc3c(c8c76)c54)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
TSHR P16473 3/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
MAPT P10636 6/20 0.32
LMNA P02545 2/20 0.32
POLB P06746 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
ACP1 P24666 1/20 0.32
TERT O14746 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ABCG2 Q9UNQ0 3/20 0.32
KDM4E B2RXH2 1/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23874715 0.99 NPC1 (0.35) NPC1RAB9ATSHRALDH1A1HPGD
SCHEMBL23875017 0.97 NPC1 (0.33) NPC1RAB9ATSHRALDH1A1HPGD
SCHEMBL23875009 0.97 NPC1 (0.33) NPC1RAB9ATSHRALDH1A1HPGD
SCHEMBL23874712 0.96 TSHR (0.35) NPC1RAB9ATSHRALDH1A1HPGD
SCHEMBL23875013 0.95 PLA2G2A (0.33) NPC1RAB9ATSHRALDH1A1HPGD
SCHEMBL23874793 0.93 NPC1 (0.38) NPC1RAB9ATSHRALDH1A1HPGD
SCHEMBL23874965 0.93 ABCG2 (0.33) NPC1RAB9ATSHRALDH1A1HPGD
SCHEMBL23874873 0.93 ABCG2 (0.34) NPC1RAB9ATSHRALDH1A1HPGD
SCHEMBL23875012 0.92 CYP1A2 (0.37) TSHRALDH1A1HPGDMAPTKMT2A
SCHEMBL23874749 0.92 TSHR (0.32) NPC1RAB9ATSHRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230165142-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-05-25 US disclosed
US-20230165142-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-05-25 US disclosed
US-20230006147-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-01-05 US disclosed
US-20220356193-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-11-10 US disclosed
US-20220173330-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-06-02 US disclosed
US-20210320263-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-14 US disclosed
US-20210305519-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220356193-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME PIEZO1, SOD1, NECTIN4 NPC1 2460/4885RAB9A 1755/4885TSHR 4813/4885
US-20230165142-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE ELAVL1, LIMS1, ZNF436-AS1 NPC1 3652/4885RAB9A 1078/4885TSHR 4730/4885
US-20230006147-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME NECTIN4, EPCAM, OR10J3 NPC1 3469/4885RAB9A 1255/4885TSHR 4798/4885
US-20220173330-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME LEF1, ODC1, OR10J3 NPC1 2166/4885RAB9A 1650/4885TSHR 4671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.