Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 12/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30058413 | 1.00 | CHRM2 (0.45) | CHRM2CHRM4CHRM1CHRM3CCNB2 | |
| SCHEMBL23875379 | 0.81 | CHRM2 (0.43) | CHRM2CHRM4CHRM1CHRM3CCNB2 | |
| SCHEMBL13696680 | 0.81 | CHRM2 (0.59) | CHRM2CHRM4CHRM1CHRM3NR1H2 | |
| SCHEMBL30022454 | 0.81 | CHRM2 (0.59) | CHRM2CHRM4CHRM1CHRM3NR1H2 | |
| SCHEMBL3203112 | 0.79 | CHRM2 (0.50) | CHRM2CHRM4CHRM1CHRM3NR1H2 | |
| SCHEMBL1920762 | 0.79 | CHRM2 (0.50) | CHRM2CHRM4CHRM1CHRM3CCNB2 | |
| SCHEMBL23875852 | 0.79 | CHRM2 (0.40) | CHRM2CHRM4CHRM1CHRM3NR1H2 | |
| SCHEMBL20226388 | 0.78 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3CCNB2 | |
| SCHEMBL15456145 | 0.78 | CDK1 (0.49) | CHRM2CHRM4CHRM1CHRM3CCNB2 | |
| SCHEMBL19164253 | 0.78 | CHRM2 (0.49) | CHRM2CHRM4CHRM1CHRM3CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2023-06-08 | — | — | US | disclosed |
| WO-2021195346-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | ALOX15B, ALOX12, ALOX15 | CHRM2 2082/4885CHRM4 3586/4885CHRM1 1983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.