Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13689141 | 0.82 | ADRA2B (0.42) | IDO1ADRA2BADRA2CTAS1R3TAS1R1 | |
| SCHEMBL18991480 | 0.82 | ADRA2B (0.44) | ADRA2BADRA2CTAS1R3TAS1R1POLB | |
| SCHEMBL11455283 | 0.79 | ADRA2B (0.40) | ADRA2BADRA2CTAS1R3TAS1R1POLB | |
| SCHEMBL2971712 | 0.78 | TAS1R3 (0.46) | IDO1TAS1R3TAS1R1POLBMAPK1 | |
| SCHEMBL13813554 | 0.77 | ADRA2B (0.46) | ADRA2BADRA2CP2RX7MEN1KMT2A | |
| SCHEMBL8679853 | 0.75 | ADRA2B (0.53) | IDO1ADRA2BADRA2CPOLBMEN1 | |
| SCHEMBL1135151 | 0.75 | ADRA2B (0.45) | ADRA2BADRA2CPOLBP2RX7 | |
| SCHEMBL22619346 | 0.74 | ADRA2B (0.44) | ADRA2BADRA2CTAS1R3TAS1R1POLB | |
| SCHEMBL7438728 | 0.74 | ALDH1A1 (0.46) | ADRA2BADRA2CTAS1R3TAS1R1POLB | |
| SCHEMBL9413635 | 0.74 | ADRA2B (0.44) | ADRA2BADRA2CTAS1R3TAS1R1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195346-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-09-30 | — | — | WO | disclosed |