Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.52 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27534985 | 0.84 | TACR1 (0.55) | HPGDCYP3A4CYP2C19POLBGAA | |
| SCHEMBL7681247 | 0.82 | LTB4R (0.51) | LTB4RLTB4R2FFAR1AOC3HPGD | |
| SCHEMBL27675321 | 0.81 | ALDH1A1 (0.56) | LTB4RLTB4R2FFAR1HPGDCYP3A4 | |
| SCHEMBL28810021 | 0.81 | ACHE (0.39) | LTB4RLTB4R2FFAR1HPGDPOLB | |
| SCHEMBL25783367 | 0.81 | TAAR1 (0.48) | AOC3GAATAAR1 | |
| SCHEMBL30530341 | 0.81 | AOC3 (0.52) | AOC3GAA | |
| SCHEMBL237091 | 0.79 | FFAR1 (0.70) | FFAR1HPGDCYP3A4CYP2C19RAB9A | |
| SCHEMBL7398650 | 0.79 | ACHE (0.60) | FFAR1HPGDCYP3A4CYP2C19RAB9A | |
| SCHEMBL1149768 | 0.79 | FFAR1 (0.70) | FFAR1HPGDCYP3A4CYP2C19RAB9A | |
| SCHEMBL237090 | 0.79 | FFAR1 (0.70) | FFAR1HPGDCYP3A4CYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195346-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-09-30 | — | — | WO | disclosed |