SCHEMBL23877482

SCHEMBL23877482

CC(C)(C)[S+]([O-])Nc1ccc(C(F)(F)F)cc1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 3/20 0.51
▸ LIPC P11150 1/20 0.50
▸ LIPG Q9Y5X9 1/20 0.50
▸ AKR1C3 P42330 4/20 0.46
▸ AKR1C2 P52895 4/20 0.46
▸ PLK1 P53350 1/20 0.45
▸ KDM4E B2RXH2 2/20 0.44
▸ ALDH1A1 P00352 2/20 0.44
▸ HPGD P15428 2/20 0.44
▸ HSD17B10 Q99714 2/20 0.44
▸ TAS2R14 Q9NYV8 2/20 0.44
▸ MPO P05164 3/20 0.43
▸ USP2 O75604 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43
▸ SORT1 Q99523 2/20 0.42
▸ AKR1B1 P15121 1/20 0.41
▸ AKR1C4 P17516 1/20 0.41
▸ AKR1C1 Q04828 1/20 0.41
▸ CDK2 P24941 1/20 0.41
▸ GRIK1 P39086 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23141296 0.86 CFTR (0.51) KDM1ALIPCLIPGKDM4EALDH1A1
SCHEMBL31496746 0.81 MEN1 (0.48) AKR1C3AKR1C2PLK1ALDH1A1
SCHEMBL3888584 0.78 LIPC (0.56) KDM1ALIPCLIPGAKR1C3AKR1C2
SCHEMBL23877470 0.78 LIPC (0.34) KDM1ALIPCLIPGPLK1
SCHEMBL3886144 0.77 LIPC (0.58) KDM1ALIPCLIPGAKR1C3AKR1C2
SCHEMBL23879628 0.77 MAPT (0.38) ALDH1A1SORT1
SCHEMBL31496755 0.76 FABP4 (0.45) AKR1C3AKR1C2KDM4EALDH1A1HPGD
SCHEMBL17627407 0.76 LIPC (0.60) KDM1ALIPCLIPGAKR1C3AKR1C2
SCHEMBL26189498 0.75 CNR2 (0.35) KDM1ALIPCLIPG
SCHEMBL3885198 0.75 KDM4E (0.59) KDM1ALIPCLIPGAKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives ORSOBIO, INC. (US) 2026-04-21 — — US disclosed
US-20240409508-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES ORSOBIO, INC. 2024-12-12 — — US disclosed
CN-118791407-A Sulfinylamino group benzamide and process for preparing same Sulfonylamino benzamide derivatives 奥索生物公司 2024-10-18 — — CN disclosed
CN-118638096-A Sulfinylamino group benzamide and process for preparing same Sulfonylamino benzamide derivatives 奥索生物公司 2024-09-13 — — CN disclosed
US-12049439-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives ORSOBIO, INC. (US) 2024-07-30 — — US disclosed
CN-112204008-B Sulfonylaminobenzamides and sulfonylaminobenzamide derivatives 奥索生物公司 2024-07-05 — — CN disclosed
EP-3796975-B1 SULFONYLAMINOBENZAMIDE DERIVATIVES ORSOBIO INC (US) 2023-08-30 — — EP disclosed
US-20220055985-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES GILEAD SCIENCES, INC. 2022-02-24 — — US disclosed
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives THE LIVER COMPANY INC. (US) 2021-10-05 — — US disclosed
CN-112204008-A Sulphonylaminobenzylamide and sulphonylaminobenzamide derivatives 吉利德科学公司 2021-01-08 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220055985-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES STS, SULT2A1, SCN2B KDM1A 2735/4885LIPC 2934/4885LIPG 3249/4885
US-12049439-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives STS, SULT2A1, SCN2B KDM1A 2735/4885LIPC 2934/4885LIPG 3249/4885
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives NR3C2, NR5A1, SRD5A2 KDM1A 4072/4885LIPC 1288/4885LIPG 3293/4885
US-20240409508-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES STS, SULT2A1, SCN2B KDM1A 2735/4885LIPC 2934/4885LIPG 3249/4885
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives STS, SULT2A1, SCN2B KDM1A 2735/4885LIPC 2934/4885LIPG 3249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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