SCHEMBL23877470

SCHEMBL23877470

CC(C)(C)[S+]([O-])Nc1ccc(C(F)(F)F)cc1C(=O)NC12CC(C(F)(F)F)(C1)C2

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LIPC P11150 1/20 0.34
▸ LIPG Q9Y5X9 1/20 0.34
▸ CETP P11597 1/20 0.33
▸ PSMB11 A5LHX3 2/20 0.33
▸ PSMA7 O14818 2/20 0.33
▸ PSMB1 P20618 2/20 0.33
▸ PSMA1 P25786 2/20 0.33
▸ PSMA2 P25787 2/20 0.33
▸ PSMA3 P25788 2/20 0.33
▸ PSMA4 P25789 2/20 0.33
▸ PSMB8 P28062 2/20 0.33
▸ PSMB9 P28065 2/20 0.33
▸ PSMA5 P28066 2/20 0.33
▸ PSMB4 P28070 2/20 0.33
▸ PSMB6 P28072 2/20 0.33
▸ PSMB5 P28074 2/20 0.33
▸ PSMB10 P40306 2/20 0.33
▸ PSMB3 P49720 2/20 0.33
▸ PSMB2 P49721 2/20 0.33
▸ PSMA6 P60900 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26189498 0.82 CNR2 (0.35) LIPCLIPGCETPPSMB11PSMA7
SCHEMBL26189285 0.81 LIPC (0.35) LIPCLIPGCETPPSMB11PSMA7
SCHEMBL22820229 0.80 KDM1A (0.40) LIPCLIPGPSMB11PSMA7PSMB1
SCHEMBL23877610 0.79 KDM1A (0.41) LIPCLIPGKDM1A
SCHEMBL23877431 0.78 CES2 (0.38) LIPCLIPGPSMB11PSMA7PSMB1
SCHEMBL23877482 0.78 KDM1A (0.51) LIPCLIPGKDM1APLK1
SCHEMBL26188606 0.77 PSMB11 (0.37) LIPCLIPGCETPPSMB11PSMA7
SCHEMBL23877527 0.77 KDM1A (0.39) LIPCLIPGPSMB11PSMA7PSMB1
SCHEMBL23877461 0.77 KIF11 (0.40) LIPCLIPGPSMB11PSMA7PSMB1
SCHEMBL31046921 0.77 DDR1 (0.38) PSMB11PSMA7PSMB1PSMA1PSMA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives ORSOBIO, INC. (US) 2026-04-21 — — US disclosed
US-20240409508-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES ORSOBIO, INC. 2024-12-12 — — US disclosed
CN-118791407-A Sulfinylamino group benzamide and process for preparing same Sulfonylamino benzamide derivatives 奥索生物公司 2024-10-18 — — CN disclosed
CN-118638096-A Sulfinylamino group benzamide and process for preparing same Sulfonylamino benzamide derivatives 奥索生物公司 2024-09-13 — — CN disclosed
US-12049439-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives ORSOBIO, INC. (US) 2024-07-30 — — US disclosed
CN-112204008-B Sulfonylaminobenzamides and sulfonylaminobenzamide derivatives 奥索生物公司 2024-07-05 — — CN disclosed
EP-3796975-B1 SULFONYLAMINOBENZAMIDE DERIVATIVES ORSOBIO INC (US) 2023-08-30 — — EP disclosed
US-20220055985-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES GILEAD SCIENCES, INC. 2022-02-24 — — US disclosed
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives THE LIVER COMPANY INC. (US) 2021-10-05 — — US disclosed
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives THE LIVER COMPANY INC. (US) 2021-10-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220055985-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES STS, SULT2A1, SCN2B LIPC 2934/4885LIPG 3249/4885CETP 4143/4885
US-12049439-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives STS, SULT2A1, SCN2B LIPC 2934/4885LIPG 3249/4885CETP 4143/4885
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives NR3C2, NR5A1, SRD5A2 LIPC 1288/4885LIPG 3293/4885CETP 2083/4885
US-20240409508-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES STS, SULT2A1, SCN2B LIPC 2934/4885LIPG 3249/4885CETP 4143/4885
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives STS, SULT2A1, SCN2B LIPC 2934/4885LIPG 3249/4885CETP 4143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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