SCHEMBL2387797

SCHEMBL2387797

CC(=O)OCCc1ccc(OC(C)=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
SMN1; SMN2 Q16637 3/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
MAPT P10636 4/20 0.47
POLB P06746 1/20 0.47
PKM P14618 1/20 0.47
PTGS2 P35354 1/20 0.47
ELANE P08246 2/20 0.46
THRB P10828 2/20 0.45
HSD17B10 Q99714 1/20 0.44
ESR1 P03372 1/20 0.44
PGR P06401 1/20 0.44
CHRM2 P08172 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
AR P10275 1/20 0.44
CHRM1 P11229 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44
GAA P10253 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9204152 0.89 LMNA (0.48) LMNASMN1; SMN2NPC1RAB9AMAPT
SCHEMBL9081470 0.86 LMNA (0.61) LMNASMN1; SMN2NPC1RAB9AMAPT
SCHEMBL17662334 0.85 LMNA (0.52) LMNASMN1; SMN2NPC1RAB9AMAPT
SCHEMBL3815839 0.85 SMN1; SMN2 (0.62) SMN1; SMN2NPC1RAB9AMAPTPOLB
SCHEMBL15164368 0.85 SMN1; SMN2 (0.55) LMNASMN1; SMN2NPC1RAB9AMAPT
SCHEMBL3392420 0.84 THRB (0.60) LMNASMN1; SMN2NPC1RAB9AMAPT
SCHEMBL18021005 0.84 LMNA (0.61) LMNASMN1; SMN2NPC1RAB9AMAPT
SCHEMBL25456089 0.82 SMN1; SMN2 (0.52) LMNASMN1; SMN2NPC1RAB9AMAPT
SCHEMBL15164370 0.82 SMN1; SMN2 (0.52) LMNASMN1; SMN2NPC1RAB9AMAPT
SCHEMBL23894744 0.82 LMNA (0.57) LMNASMN1; SMN2NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3833366-B1 MICROORGANISM MIXTURES, MOLECULES DERIVED THEREFROM, AND METHODS OF USE THEREOF B G NEGEV TECHNOLOGIES AND APPLICATIONS LTD AT BEN GURION UNIV (IL) 2025-12-03 EP claimed
US-12478610-B2 Compositions of tryptophol derivatives and 4-ethyl-phenol derivatives, and methods of using same MALKA, Orit (IL) 2025-11-25 US claimed
EP-4561550-A1 THERAPEUTIC EFFECT OF MOLECULES DERIVED FROM PROBIOTIC MILK-BASED FERMENTATION MICROBIAL CONSORTIUM (\"KEFIR\") ON WOUNDS HEALING B.G. Negev Technologies and Applications Ltd., at Ben-Gurion University (IL) 2025-06-04 EP claimed
US-20240041829-A1 METHODS FOR MODULATING MICROBIAL POPULATIONS BAR-ILAN UNIVERSITY (IL) 2024-02-08 US claimed
EP-4267120-A1 METHODS FOR MODULATING MICROBIAL POPULATIONS B.G. Negev Technologies and Applications Ltd., at Ben-Gurion University (IL) 2023-11-01 EP claimed
CN-116672274-A Use of sweetsop fermentation liquor for preparing composition for inhibiting melanin generation and improving immune cell antioxidant capacity 百岳特生物技术(上海)有限公司 2023-09-01 CN claimed
US-20230172905-A1 COMPOSITIONS OF TRYPTOPHOL DERIVATIVES AND 4-ETHYL-PHENOL DERIVATIVES, AND METHODS OF USING SAME B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) 2023-06-08 US claimed
EP-4149458-A1 COMPOSITIONS OF TRYPTOPHOL DERIVATIVES AND 4-ETHYL-PHENOL DERIVATIVES, AND METHODS OF USING SAME B.G. Negev Technologies and Applications Ltd., at Ben-Gurion University (IL) 2023-03-22 EP claimed
WO-2022137239-A1 METHODS FOR MODULATING MICROBIAL POPULATIONS B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) 2022-06-30 WO claimed
US-20220160680-A1 MICROORGANISM MIXTURES, MOLECULES DERIVED THEREFROM, AND METHODS OF USE THEREOF B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) 2022-05-26 US claimed
EP-3833366-B1 MICROORGANISM MIXTURES, MOLECULES DERIVED THEREFROM, AND METHODS OF USE THEREOF B G NEGEV TECHNOLOGIES AND APPLICATIONS LTD AT BEN GURION UNIV (IL) 2025-12-03 EP disclosed
US-12478610-B2 Compositions of tryptophol derivatives and 4-ethyl-phenol derivatives, and methods of using same MALKA, Orit (IL) 2025-11-25 US disclosed
EP-4561550-A1 THERAPEUTIC EFFECT OF MOLECULES DERIVED FROM PROBIOTIC MILK-BASED FERMENTATION MICROBIAL CONSORTIUM (\"KEFIR\") ON WOUNDS HEALING B.G. Negev Technologies and Applications Ltd., at Ben-Gurion University (IL) 2025-06-04 EP disclosed
CN-114195640-B Synthesis process of hydroxytyrosol and intermediate thereof 攀枝花学院 2024-03-12 CN disclosed
US-20240041829-A1 METHODS FOR MODULATING MICROBIAL POPULATIONS BAR-ILAN UNIVERSITY (IL) 2024-02-08 US disclosed
EP-0625971-A1 UV LIGHT STABILIZING, ANTIOXIDANT AND COLORANT COMPOUNDS HOECHST CELANESE CORPORATION (US) 1994-11-30 EP disclosed
US-5247124-A Process for the preparation of substituted styrenes HOECHST CELANESE CORPORATION (US) 1993-09-21 US disclosed
WO-1993015063-A1 UV LIGHT STABILIZING, ANTIOXIDANT AND COLORANT COMPOUNDS HOECHST CELANESE CORPORATION (US) 1993-08-05 WO disclosed
US-5210278-A Process for the preparation of bisarylalkyl ethers HOECHST CELANESE CORPORATION (US) 1993-05-11 US disclosed
US-5194672-A Process for the preparation of substituted styrenes HOECHST CELANESE CORPORATION (US) 1993-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12478610-B2 Compositions of tryptophol derivatives and 4-ethyl-phenol derivatives, and methods of using same F2, TYR, TH LMNA 1871/4885SMN1; SMN2 4343/4885NPC1 4489/4885
US-20220160680-A1 MICROORGANISM MIXTURES, MOLECULES DERIVED THEREFROM, AND METHODS OF USE THEREOF COMT, TH, TDO2 LMNA 3885/4885SMN1; SMN2 4812/4885NPC1 4369/4885
US-20230172905-A1 COMPOSITIONS OF TRYPTOPHOL DERIVATIVES AND 4-ETHYL-PHENOL DERIVATIVES, AND METHODS OF USING SAME F2, TYR, TH LMNA 1871/4885SMN1; SMN2 4343/4885NPC1 4489/4885
US-20240041829-A1 METHODS FOR MODULATING MICROBIAL POPULATIONS TYR, TPH2, IDO2 LMNA 4154/4885SMN1; SMN2 4863/4885NPC1 3820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.