Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | RRM1 | P23921 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23882001 | 1.00 | CES2 (0.47) | CES2TSHRFAAHMEN1TP53 | |
| SCHEMBL936123 | 1.00 | CES2 (0.47) | CES2TSHRFAAHMEN1TP53 | |
| SCHEMBL20243493 | 1.00 | CES2 (0.47) | CES2TSHRFAAHMEN1TP53 | |
| SCHEMBL20241158 | 0.84 | BHMT (0.44) | TSHRMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL27394525 | 0.84 | SLC15A1 (0.46) | CES2TSHRFAAHCHRM2CHRM4 | |
| SCHEMBL20243486 | 0.84 | BHMT (0.44) | TSHRMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL904746 | 0.83 | CES2 (0.55) | CES2CHRM2CHRM4CHRM1 | |
| SCHEMBL5319167 | 0.83 | CES2 (0.55) | CES2CHRM2CHRM4CHRM1RRM1 | |
| SCHEMBL17374802 | 0.83 | CES2 (0.55) | CES2CHRM2CHRM4CHRM1 | |
| SCHEMBL11395919 | 0.83 | CES2 (0.55) | CES2CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126004-A1 | AGONIST COMBINATION | Zealand Pharma A/S (DK) | 2023-02-08 | — | — | EP | disclosed |
| WO-2021198195-A1 | AGONIST COMBINATION | ZEALAND PHARMA A/S (DK) | 2021-10-07 | — | — | WO | disclosed |