Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10285197 | 0.81 | THRA (0.41) | HPGDSMEN1KMT2ALMNAKDM4E | |
| SCHEMBL624930 | 0.81 | SMN1; SMN2 (0.61) | HPGDSMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL21755483 | 0.81 | MEN1 (0.63) | HPGDSMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL4355417 | 0.81 | HPGDS (0.55) | HPGDSMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL3465985 | 0.81 | HPGDS (0.55) | HPGDSMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL29799615 | 0.81 | SMN1; SMN2 (0.61) | HPGDSMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1435371 | 0.80 | HPGDS (0.54) | HPGDSMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL31605249 | 0.80 | HPGDS (0.54) | HPGDSMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1121702 | 0.80 | NPC1 (0.55) | HPGDSMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL257236 | 0.79 | ALDH1A1 (0.62) | SMN1; SMN2HTTRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888651-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | Kyushu University, National University Corporation (JP) | 2021-10-06 | — | — | EP | disclosed |