Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 4/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110731 | 0.84 | SMN1; SMN2 (0.44) | THRATHRBPTPN11S1PR3CNR1 | |
| SCHEMBL13637552 | 0.82 | FAAH (0.43) | THRATHRBPTPN11S1PR3CNR1 | |
| SCHEMBL23888902 | 0.81 | HPGDS (0.54) | HPGDSKMT2AMEN1LMNAMAPT | |
| SCHEMBL5055118 | 0.80 | LMNA (0.59) | THRBPTPN11CNR1CNR2KMT2A | |
| SCHEMBL21436837 | 0.76 | MAOB (0.56) | CYP3A4MAOBTSHRTDP1L3MBTL1 | |
| SCHEMBL16378277 | 0.76 | CYP1A2 (0.44) | KMT2AMEN1LMNACYP3A4MAPT | |
| SCHEMBL15766880 | 0.75 | LMNA (0.68) | THRATHRBPTPN11S1PR3CNR1 | |
| SCHEMBL22568104 | 0.75 | TDP1 (0.49) | MAPTMAOBTDP1L3MBTL1CYP1A2 | |
| SCHEMBL11461787 | 0.75 | LMNA (0.68) | THRATHRBPTPN11S1PR3CNR1 | |
| SCHEMBL11259348 | 0.75 | LMNA (0.68) | THRATHRBPTPN11S1PR3CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2407459-A1 | Synthetic intermediate in the production of a sulfonamide derivative having PGD2 receptor antagonistic activity | Shionogi & Co., Ltd. (JP) | 2012-01-18 | — | — | EP | disclosed |