Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 19/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19127918 | 0.89 | L3MBTL1 (0.44) | CFDL3MBTL1 | |
| SCHEMBL20646911 | 0.86 | HTR3A (0.39) | CFDL3MBTL1 | |
| SCHEMBL12479695 | 0.81 | CFD (0.50) | CFD | |
| SCHEMBL24247735 | 0.80 | CFD (0.50) | CFD | |
| SCHEMBL16471699 | 0.79 | L3MBTL1 (0.51) | CFDL3MBTL1 | |
| SCHEMBL17324779 | 0.79 | ROCK1 (0.48) | CFD | |
| SCHEMBL17176468 | 0.78 | HTR3A (0.58) | CFD | |
| Trifluoroacetic Acid SCHEMBL13836726 | 0.78 | CFD (0.49) | CFD | |
| SCHEMBL24247699 | 0.78 | L3MBTL1 (0.43) | L3MBTL1 | |
| SCHEMBL10126774 | 0.76 | PTGDR2 (0.53) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3954681-A1 | SPIROHEPTANE SALICYLAMIDES AND RELATED COMPOUNDS AS INHIBITORS OF ROCK | Bristol-Myers Squibb Company (US) | 2022-02-16 | — | — | EP | disclosed |
| EP-3402790-B1 | SPIROHEPTANE SALICYLAMIDES AND RELATED COMPOUNDS AS INHIBITORS OF ROCK | BRISTOL MYERS SQUIBB CO (US) | 2021-10-06 | — | — | EP | disclosed |