Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28436985 | 0.81 | DRD2 (0.46) | OPRM1MEN1KMT2ADRD2PIK3CA | |
| SCHEMBL29914669 | 0.81 | DRD2 (0.46) | OPRM1MEN1KMT2ADRD2PIK3CA | |
| SCHEMBL27865440 | 0.81 | DRD2 (0.46) | OPRM1MEN1KMT2ADRD2PIK3CA | |
| SCHEMBL23731861 | 0.81 | ADRB1 (0.50) | MAPTHSD17B10TSHRALDH1A1 | |
| SCHEMBL13972914 | 0.81 | ADRA2C (0.51) | MEN1KMT2AMAPTPIK3CAHSD17B10 | |
| SCHEMBL2722659 | 0.79 | HTR3E (0.50) | KMT2AMAPTHSD17B10ALDH1A1HTR7 | |
| SCHEMBL2722663 | 0.79 | HTR3E (0.50) | KMT2AMAPTHSD17B10ALDH1A1HTR7 | |
| SCHEMBL10182584 | 0.79 | HTR3E (0.50) | KMT2AMAPTHSD17B10ALDH1A1HTR7 | |
| SCHEMBL14321601 | 0.79 | HSD17B10 (0.60) | MEN1KMT2AMAPTHSD17B10TSHR | |
| SCHEMBL14321602 | 0.79 | HSD17B10 (0.60) | MEN1KMT2AMAPTHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269960-A1 | TRIAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-11-03 | — | — | US | disclosed |
| US-20110269960-A1 | TRIAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-11-03 | — | — | US | disclosed |
| US-20110269960-A1 | TRIAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-11-03 | — | — | US | disclosed |
| US-8022091-B2 | Triazole derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-8022091-B2 | Triazole derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-8022091-B2 | Triazole derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20100041655-A1 | TRIAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2010-02-18 | — | — | US | disclosed |
| US-20100041655-A1 | TRIAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2010-02-18 | — | — | US | disclosed |
| US-20100041655-A1 | TRIAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2010-02-18 | — | — | US | disclosed |
| EP-1988083-A1 | TRIAZOLE DERIVATIVE | Taisho Pharmaceutical Co. Ltd. (JP) | 2008-11-05 | — | — | EP | disclosed |
| EP-1988083-A1 | TRIAZOLE DERIVATIVE | Taisho Pharmaceutical Co. Ltd. (JP) | 2008-11-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269960-A1 | TRIAZOLE DERIVATIVE | S1PR3, S1PR1, S1PR5 | OPRM1 1465/4885MEN1 1062/4885KMT2A 1641/4885 |
| US-20100041655-A1 | TRIAZOLE DERIVATIVE | S1PR3, S1PR1, S1PR5 | OPRM1 1412/4885MEN1 1061/4885KMT2A 1630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.