Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 3/20 | 0.41 |
| ▸ | BCR | P11274 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472686 | 0.82 | VCAM1 (0.62) | VCAM1ALDH1A1HIF1AALDH5A1ABAT | |
| SCHEMBL22040900 | 0.81 | VCAM1 (0.54) | VCAM1ALDH1A1HIF1AVCPALDH5A1 | |
| SCHEMBL14880649 | 0.80 | ALDH1A1 (0.60) | VCAM1ALDH1A1HIF1AVCPALDH5A1 | |
| SCHEMBL9656171 | 0.80 | VCAM1 (0.70) | VCAM1ALDH1A1ALDH5A1ABATMAPT | |
| SCHEMBL3499951 | 0.80 | NFE2L2 (0.56) | VCAM1ALDH1A1HIF1AVCPMAPT | |
| SCHEMBL11663744 | 0.80 | VCAM1 (0.70) | VCAM1ALDH1A1ALDH5A1ABATMAPT | |
| SCHEMBL3499948 | 0.80 | NFE2L2 (0.56) | VCAM1ALDH1A1HIF1AVCPMAPT | |
| SCHEMBL15709537 | 0.78 | PLA2G4A (0.59) | VCAM1ALDH1A1HIF1AMAPTLMNA | |
| SCHEMBL1903142 | 0.78 | PLA2G4A (0.59) | VCAM1ALDH1A1HIF1AMAPTLMNA | |
| SCHEMBL1903144 | 0.78 | PLA2G4A (0.59) | VCAM1ALDH1A1HIF1AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889138-A1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2021-10-06 | — | — | EP | disclosed |