SCHEMBL2389199

SCHEMBL2389199

c1ccc(-c2cccc(N(c3ccccc3)c3ccc4c(c3)Oc3ccc(N(c5ccccc5)c5cccc(-c6ccccc6)c5)cc3O4)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MAPT P10636 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
AHR P35869 3/20 0.36
MGLL Q99685 1/20 0.35
MAOA P21397 1/20 0.34
CA12 O43570 1/20 0.34
CA9 Q16790 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
GAA P10253 2/20 0.33
CRHBP P24387 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12259304 1.00 ALDH1A1 (0.38) ALDH1A1KDM4EL3MBTL1MAPTCYP2C9
SCHEMBL12259278 0.98 AHR (0.37) ALDH1A1KDM4EL3MBTL1MAPTCYP2C9
SCHEMBL18563248 0.91 AHR (0.41) ALDH1A1KDM4EL3MBTL1MAPTCYP2C9
SCHEMBL18563259 0.89 AHR (0.42) ALDH1A1KDM4EL3MBTL1MAPTCYP2C9
SCHEMBL18563290 0.89 AHR (0.42) ALDH1A1KDM4EL3MBTL1MAPTCYP2C9
SCHEMBL18563227 0.89 AHR (0.42) ALDH1A1KDM4EL3MBTL1MAPTCYP2C9
SCHEMBL22180111 0.89 ALDH1A1 (0.46) ALDH1A1KDM4EL3MBTL1MAPTCYP2C9
SCHEMBL24277679 0.89 KDM4E (0.37) ALDH1A1KDM4EL3MBTL1MAPTCYP2C9
SCHEMBL24277681 0.89 KDM4E (0.37) ALDH1A1KDM4EL3MBTL1MAPTCYP2C9
SCHEMBL16787279 0.88 AHR (0.41) ALDH1A1KDM4EL3MBTL1MAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11211565-B2 Condensed-cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-12-28 US disclosed
EP-2984079-B1 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES POWER OLEDS LTD (GB) 2020-07-01 EP disclosed
US-10439147-B2 Heterocyclic compounds and their use in electro-optical or opto-electronic devices POWER OLEDS LIMITED (GB) 2019-10-08 US disclosed
US-10361373-B2 Condensed-cyclic compound and organic light emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-23 US disclosed
US-20190140184-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-05-09 US disclosed
US-20180323378-A9 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES POWER OLEDS LIMITED (GB) 2018-11-08 US disclosed
US-20170062720-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-02 US disclosed
US-20170062720-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-02 US disclosed
EP-2984079-A2 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES Power Oleds Limited (GB) 2016-02-17 EP disclosed
US-20160035983-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES POWER OLEDS LTD (GB) 2016-02-04 US disclosed
WO-2014167286-A2 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES POWER OLEDS LIMITED (GB) 2014-10-16 WO disclosed
US-8012606-B2 Heterocyclic compound and organic electroluminescent device using the same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2011-09-06 US disclosed
US-8012606-B2 Heterocyclic compound and organic electroluminescent device using the same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2011-09-06 US disclosed
US-8012606-B2 Heterocyclic compound and organic electroluminescent device using the same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2011-09-06 US disclosed
US-20090153031-A1 Heterocyclic compound and organic electroluminescent device using the same NIPPON STEEL CHEMICAL CO., LTD (JP) 2009-06-18 US disclosed
US-20090153031-A1 Heterocyclic compound and organic electroluminescent device using the same NIPPON STEEL CHEMICAL CO., LTD (JP) 2009-06-18 US disclosed
US-20090153031-A1 Heterocyclic compound and organic electroluminescent device using the same NIPPON STEEL CHEMICAL CO., LTD (JP) 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170062720-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LRRK2, SLC18A1, CCNT1 ALDH1A1 832/4885KDM4E 1389/4885L3MBTL1 377/4885
US-20180323378-A9 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES NAT1, SLCO2A1, SLCO2B1 ALDH1A1 789/4885KDM4E 4166/4885L3MBTL1 899/4885
US-10439147-B2 Heterocyclic compounds and their use in electro-optical or opto-electronic devices NAT1, SLCO2A1, SLCO2B1 ALDH1A1 789/4885KDM4E 4166/4885L3MBTL1 899/4885
US-20190140184-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 ALDH1A1 278/4885KDM4E 3637/4885L3MBTL1 1793/4885
US-20160035983-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES NAT1, SLCO2A1, SLCO2B1 ALDH1A1 789/4885KDM4E 4166/4885L3MBTL1 899/4885
US-11211565-B2 Condensed-cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 ALDH1A1 278/4885KDM4E 3637/4885L3MBTL1 1793/4885
US-20090153031-A1 Heterocyclic compound and organic electroluminescent device using the same ORC3, NAP1L4, NR4A2 ALDH1A1 1372/4885KDM4E 1619/4885L3MBTL1 1984/4885
US-10361373-B2 Condensed-cyclic compound and organic light emitting device comprising the same LRRK2, SLC18A1, CCNT1 ALDH1A1 832/4885KDM4E 1389/4885L3MBTL1 377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.