Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 6/20 | 0.62 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | GLS | O94925 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2388252 | 0.83 | RAB9A (0.64) | KDM4EUSP2ALDH1A1EPHX2NPC1 | |
| SCHEMBL362394 | 0.80 | ALDH1A1 (0.66) | PSMB8ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13766306 | 0.77 | SMN1; SMN2 (0.58) | ROCK2PSMB8POLBHPGDCYP1A2 | |
| SCHEMBL17783810 | 0.77 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL14073604 | 0.77 | ROCK2 (0.60) | ROCK2PSMB8ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14073866 | 0.77 | ROCK2 (0.63) | ROCK2PSMB8CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10759415 | 0.77 | PSMB8 (0.55) | ROCK2PSMB8KDM4EUSP2ALDH1A1 | |
| SCHEMBL25810554 | 0.77 | MEN1 (0.57) | ROCK2PSMB8ALDH1A1HPGDCYP1A2 | |
| SCHEMBL25380516 | 0.76 | CFD (0.62) | PSMB8KDM4EUSP2ALDH1A1ESR1 | |
| SCHEMBL30510132 | 0.76 | CFD (0.62) | PSMB8KDM4EUSP2ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012606-B2 | Heterocyclic compound and organic electroluminescent device using the same | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20090153031-A1 | Heterocyclic compound and organic electroluminescent device using the same | NIPPON STEEL CHEMICAL CO., LTD (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090153031-A1 | Heterocyclic compound and organic electroluminescent device using the same | ORC3, NAP1L4, NR4A2 | ROCK2 3060/4885PSMB8 2545/4885KDM4E 1619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.