Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.42 |
| ▸ | CLK1 | P49759 | 3/20 | 0.42 |
| ▸ | CLK2 | P49760 | 3/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | CLK3 | P49761 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 5/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2390459 | 0.80 | KDM4E (0.48) | DYRK1ACLK4CLK1CLK2DYRK1B | |
| SCHEMBL2388344 | 0.77 | MAPK1 (0.59) | CDK2CCNA2MAPK3MAPK1RET | |
| SCHEMBL2387413 | 0.77 | CNR2 (0.45) | CDK2CCNA2MAPK3MAPK1MTOR | |
| SCHEMBL2389822 | 0.70 | IKBKB (0.55) | DYRK1ADYRK1BCDK2CCNA2MAPK3 | |
| SCHEMBL27843897 | 0.70 | DYRK1A (0.49) | DYRK1ACLK4CLK1CLK2DYRK1B | |
| SCHEMBL26819168 | 0.69 | KCNH3 (0.44) | DYRK1ACLK4CLK1CLK2DYRK1B | |
| SCHEMBL7449145 | 0.68 | VCP (0.57) | VCPCLK4USP30CDK2MAPK1 | |
| SCHEMBL2578413 | 0.67 | HRH4 (0.55) | VCPCLK4USP30CDK2MAPK1 | |
| SCHEMBL38657931 | 0.67 | CDK2 (0.50) | DYRK1ACLK4CLK1CLK2DYRK1B | |
| SCHEMBL30850578 | 0.67 | GRM4 (0.46) | DYRK1ACLK4CLK1CLK2DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205086-B1 | FUNGICIDAL HETEROCYCLIC AMINES | DU PONT (US) | 2013-08-14 | — | — | EP | disclosed |
| US-20110301123-A1 | Fungicidal Heterocyclic Amines | E.I. DU PONT NEMOURS AND COMPANY (US) | 2011-12-08 | — | — | US | disclosed |
| US-8026359-B2 | Fungicidal heterocyclic amines | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-27 | — | — | US | disclosed |
| US-20100267729-A1 | FUNGICIDAL HETEROCYCLIC AMINES | E.I. DU PONT DE NEMOURS AND COMPANY (DE) | 2010-10-21 | — | — | US | disclosed |
| EP-2205086-A2 | FUNGICIDAL HETEROCYCLIC AMINES | E. I. du Pont de Nemours and Company (US) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009061761-A2 | FUNGICIDAL HETEROCYCLIC AMINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267729-A1 | FUNGICIDAL HETEROCYCLIC AMINES | PRMT9, MAOB, CYP2C9 | VCP 3355/4885DYRK1A 3451/4885CLK4 4410/4885 |
| US-20110301123-A1 | Fungicidal Heterocyclic Amines | PRMT9, MAOB, CYP2C9 | VCP 3355/4885DYRK1A 3451/4885CLK4 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.