Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13080778 | 0.82 | ELANE (0.42) | ELANEKDM4EPOLBATML3MBTL1 | |
| SCHEMBL10173403 | 0.73 | ELANE (0.42) | ELANEKDM4EPOLB | |
| SCHEMBL23843283 | 0.68 | ELANE (0.32) | ELANE | |
| SCHEMBL24006183 | 0.65 | HTR1B (0.38) | ELANEKDM4EPDE10A | |
| SCHEMBL12309182 | 0.65 | ELANE (0.49) | ELANEKDM4EPOLB | |
| SCHEMBL23959345 | 0.64 | PDE10A (0.33) | ELANEKDM4EPDE10A | |
| SCHEMBL17407845 | 0.64 | NOS3 (0.33) | — | |
| SCHEMBL22095159 | 0.62 | NOS3 (0.34) | ELANEKDM4E | |
| SCHEMBL15316715 | 0.62 | HMGCR (0.35) | KDM4E | |
| SCHEMBL12318130 | 0.62 | LMNA (0.40) | ELANEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210308276-A1 | HETEROARYL SULFONE-BASED CONJUGATION HANDLES, METHODS FOR THEIR PREPARATION, AND THEIR USE IN SYNTHESIZING ANTIBODY DRUG CONJUGATES | PFIZER INC. (US) | 2021-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210308276-A1 | HETEROARYL SULFONE-BASED CONJUGATION HANDLES, METHODS FOR THEIR PREPARATION, AND THEIR USE IN SYNTHESIZING ANTIBODY DRUG CONJUGATES | SULT1E1, FCGRT, SULT2A1 | ELANE 3979/4885KDM4E 811/4885POLB 3958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.