Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18572173 | 0.80 | ABL1 (0.54) | YTHDC1TP53LMNAPRMT5WDR77 | |
| SCHEMBL22187775 | 0.79 | PI4KA (0.43) | PRMT5WDR77EGFRKDM4EMEN1 | |
| SCHEMBL22509955 | 0.79 | PDPK1 (0.43) | YTHDC1TP53LMNAPRMT5WDR77 | |
| SCHEMBL22858487 | 0.79 | YTHDC1 (0.42) | YTHDC1TP53LMNAPRMT5WDR77 | |
| SCHEMBL21473730 | 0.77 | CCNB2 (0.43) | YTHDC1TP53LMNAPRMT5WDR77 | |
| SCHEMBL22521390 | 0.76 | YTHDC1 (0.40) | YTHDC1TP53LMNAPRMT5WDR77 | |
| SCHEMBL8970970 | 0.69 | YTHDC1 (0.66) | YTHDC1PDE5APDE4APDE1APDE1B | |
| SCHEMBL25996807 | 0.68 | ABL1 (0.39) | YTHDC1TP53LMNAPRMT5WDR77 | |
| SCHEMBL25996757 | 0.67 | ALDH1A1 (0.38) | TP53LMNAPRMT5WDR77ABL1 | |
| SCHEMBL17875203 | 0.67 | PRMT5 (0.47) | YTHDC1PRMT5WDR77ABL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283434-A9 | AMINOOXY CLICK CHEMISTRY (AOCC): A VERSATILE BIOCONJUGATION APPROACH | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-03-28 | — | — | WO | disclosed |
| WO-2023069495-A1 | OLIGONUCLEOTIDES WITH 2'-DEOXY-2'-F-2'-C-METHYL NUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| WO-2023283434-A1 | AMINOOXY CLICK CHEMISTRY (AOCC): A VERSATILE BIOCONJUGATION APPROACH | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-01-12 | — | — | WO | disclosed |
| WO-2021202511-A2 | MICROTUBULE ASSOCIATED PROTEIN TAU (MAPT) iRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF | ALNYLAM PHARMACEUTICALS, INC. (US) | 2021-10-07 | — | — | WO | disclosed |