Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18572173 | 0.80 | ABL1 (0.54) | YTHDC1TP53LMNAPRMT5WDR77 | |
| SCHEMBL22509955 | 0.79 | PDPK1 (0.43) | YTHDC1TP53LMNAPRMT5WDR77 | |
| SCHEMBL23898962 | 0.79 | YTHDC1 (0.42) | YTHDC1TP53LMNAPRMT5WDR77 | |
| SCHEMBL21473730 | 0.77 | CCNB2 (0.43) | YTHDC1TP53LMNAPRMT5WDR77 | |
| SCHEMBL22521390 | 0.76 | YTHDC1 (0.40) | YTHDC1TP53LMNAPRMT5WDR77 | |
| SCHEMBL24720081 | 0.76 | PRMT5 (0.44) | YTHDC1TP53LMNAPRMT5WDR77 | |
| SCHEMBL24205545 | 0.75 | PRMT5 (0.48) | YTHDC1TP53LMNAPRMT5WDR77 | |
| SCHEMBL22508902 | 0.72 | SLC22A12 (0.44) | PRMT5WDR77SRCMEN1ALDH1A1 | |
| SCHEMBL24205320 | 0.71 | PDPK1 (0.41) | YTHDC1TP53LMNAPRMT5WDR77 | |
| SCHEMBL20041716 | 0.69 | YTHDC1 (0.66) | YTHDC1PDE5APDE4APDE1APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002720-A1 | DNA SEQUENCING REACTION ADDITIVE | IsoPlexis Corporation | 2021-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002720-A1 | DNA SEQUENCING REACTION ADDITIVE | RNGTT, NSUN2, NT5C3B | YTHDC1 631/4885TP53 975/4885LMNA 3089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.