Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 15/20 | 0.40 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.32 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.32 |
| ▸ | CLK1 | P49759 | 2/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31391685 | 1.00 | NTRK1 (0.40) | NTRK1NTRK3NTRK2CLK1DYRK1A | |
| SCHEMBL23901315 | 0.72 | FGFR1 (0.40) | NTRK1DYRK1A | |
| SCHEMBL31391737 | 0.72 | FGFR1 (0.40) | NTRK1DYRK1A | |
| SCHEMBL16525301 | 0.66 | GABRP (0.43) | — | |
| SCHEMBL29732425 | 0.66 | DYRK1A (0.33) | NTRK2DYRK1A | |
| SCHEMBL12481324 | 0.66 | PIM1 (0.33) | DYRK1A | |
| SCHEMBL14688819 | 0.66 | DYRK1A (0.33) | NTRK2DYRK1A | |
| SCHEMBL35211471 | 0.66 | TRPA1 (0.41) | DYRK1A | |
| SCHEMBL28810940 | 0.65 | IDO1 (0.35) | NTRK1CLK1DYRK1A | |
| SCHEMBL1553551 | 0.64 | ITK (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021197467-A1 | MULTI-TARGET ANTI-TUMOR COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海华汇拓医药科技有限公司 | 2021-10-07 | — | — | WO | disclosed |