Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 3/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.31 |
| ▸ | FEN1 | P39748 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384229 | 0.74 | GABRP (0.44) | IDO1BACE1NTRK1NOS3 | |
| SCHEMBL28091212 | 0.73 | MEN1 (0.46) | MEN1KMT2AALOX5APFEN1 | |
| SCHEMBL28046258 | 0.73 | NOS1 (0.40) | IDO1BACE1NOS3NOS1 | |
| SCHEMBL12963770 | 0.69 | — | — | |
| SCHEMBL14814345 | 0.67 | CLK1 (0.37) | CLK1DYRK1ANTRK1 | |
| SCHEMBL5251885 | 0.67 | IDO1 (0.50) | IDO1NTRK1 | |
| SCHEMBL379466 | 0.67 | FEN1 (0.47) | ALOX5APFEN1 | |
| SCHEMBL28281085 | 0.67 | CYP11B1 (0.36) | IDO1NTRK1 | |
| SCHEMBL19792419 | 0.66 | — | — | |
| SCHEMBL16346569 | 0.66 | NOS2 (0.47) | MEN1KMT2ADYRK1ANTRK1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901280-B | MrgprX2 antagonists and uses thereof | 德米拉公司 | 2025-05-27 | — | — | CN | disclosed |
| EP-4054570-A1 | MRGPRX2 ANTAGONISTS AND USES THEREOF | Dermira, Inc (US) | 2022-09-14 | — | — | EP | disclosed |
| CN-114901280-A | MrgprX2 antagonists and uses thereof | 德米拉公司 | 2022-08-12 | — | — | CN | disclosed |