Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 7/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30780103 | 1.00 | KDM4E (0.50) | KDM4EHCAR3GRIN2DGRIN2AGRIN2B | |
| SCHEMBL17631570 | 0.86 | RAB9A (0.48) | KDM4EABL1 | |
| SCHEMBL16742070 | 0.82 | PIM1 (0.51) | PIM1CSNK2A1PIM2PIM3PIK3CD | |
| SCHEMBL1663456 | 0.81 | HCAR3 (0.55) | KDM4EHCAR3PIM3 | |
| SCHEMBL15226864 | 0.81 | KDM4E (0.54) | KDM4EPIM1CSNK2A1PIM3DYRK3 | |
| SCHEMBL26885120 | 0.80 | ALDH1A1 (0.55) | KDM4EGRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL9911523 | 0.79 | ALDH1A1 (0.56) | KDM4E | |
| SCHEMBL30607064 | 0.79 | ALDH1A1 (0.56) | KDM4E | |
| SCHEMBL26885174 | 0.77 | KDM4E (0.56) | KDM4EGRIN2DGRIN2AGRIN2BGRIN2C | |
| Methyl Alcohol SCHEMBL7181550 | 0.77 | KDM4E (0.69) | KDM4EGRIN2DGRIN2AGRIN2BGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025086591-A1 | ROTIGOTINE PRODRUG DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 烟台药物研究所 | 2025-05-01 | — | — | WO | disclosed |
| CN-117105906-B | Rotigotine prodrug derivatives, pharmaceutical compositions and uses thereof | 烟台药物研究所 | 2024-01-30 | — | — | CN | disclosed |
| CN-117105906-A | Rotigotine prodrug derivatives, pharmaceutical compositions and uses thereof | 烟台药物研究所 | 2023-11-24 | — | — | CN | disclosed |
| US-20230143470-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | NATIONAL INSTITUTES OF HEALTH | 2023-05-11 | — | — | US | disclosed |
| US-20230143470-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | NATIONAL INSTITUTES OF HEALTH | 2023-05-11 | — | — | US | disclosed |
| WO-2021202600-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230143470-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | HAVCR2, CD44, ENGASE | KDM4E 4478/4885HCAR3 764/4885GRIN2D 4874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.