Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194039 | 0.84 | RXFP1 (0.53) | HCAR3TDP1TSHRALDH1A1LMNA | |
| SCHEMBL6237516 | 0.83 | TP53 (0.48) | HCAR3TDP1TSHRTP53ALDH1A1 | |
| SCHEMBL22071184 | 0.83 | TP53 (0.48) | HCAR3TDP1TSHRTP53ALDH1A1 | |
| SCHEMBL350280 | 0.83 | TP53 (0.48) | HCAR3TDP1TSHRTP53ALDH1A1 | |
| SCHEMBL350279 | 0.83 | TP53 (0.48) | HCAR3TDP1TSHRTP53ALDH1A1 | |
| SCHEMBL10055051 | 0.83 | RXFP1 (0.56) | TDP1TSHRTP53ALDH1A1LMNA | |
| SCHEMBL1615179 | 0.82 | ALDH1A1 (0.65) | TDP1TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL31572047 | 0.82 | ALDH1A1 (0.69) | HCAR3TDP1TSHRTP53ALDH1A1 | |
| SCHEMBL23901559 | 0.81 | KDM4E (0.50) | HCAR3KDM4EPIM3 | |
| SCHEMBL30780103 | 0.81 | KDM4E (0.50) | HCAR3KDM4EPIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025086591-A1 | ROTIGOTINE PRODRUG DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 烟台药物研究所 | 2025-05-01 | — | — | WO | disclosed |
| US-11827640-B2 | Substituted pyrazolo[1,5-a]pyrimidines as CFTR modulators | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2023-11-28 | — | — | US | disclosed |
| CN-115583946-A | Heterocyclic compounds and their use as CDK inhibitors | 赛诺哈勃药业（成都）有限公司 | 2023-01-10 | — | — | CN | disclosed |
| US-11198705-B2 | Hybrid Amphotericin B derivatives with reduced toxicity | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-12-14 | — | — | US | disclosed |
| US-10882883-B2 | Derivatives of amphotericin B | SFUNGA THERAPEUTICS, INC. (US) | 2021-01-05 | — | — | US | disclosed |
| US-20200262858-A1 | DERIVATIVES OF AMPHOTERICIN B | ELION THERAPEUTICS, INC. | 2020-08-20 | — | — | US | disclosed |
| US-10604492-B2 | CFTR regulators and methods of use thereof | THE REGENTS OF THE UNIVERSTIY OF CALIFORNIA (US) | 2020-03-31 | — | — | US | disclosed |
| WO-2017196261-A1 | JAK AND HDAC DUAL-INHIBITOR COMPOUNDS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2017-11-16 | — | — | WO | disclosed |
| US-20170247340-A1 | Inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase and Uses Thereof | LA JOLLA INSTITUTE OF ALLERGY & IMMUNOLOGY | 2017-08-31 | — | — | US | disclosed |
| US-9622991-B2 | Hematopoietic growth factor mimetic small molecule compounds and their uses | LIGAND PHARMACEUTICALS INC. (US) | 2017-04-18 | — | — | US | disclosed |
| EP-1477537-B1 | Ink-jet recording method | KONICA MINOLTA MED & GRAPHIC (JP) | 2008-05-14 | — | — | EP | disclosed |
| EP-1630213-B1 | Ink-jet ink set and recording method using the same | KONICA MINOLTA MED & GRAPHIC (JP) | 2008-01-09 | — | — | EP | disclosed |
| US-20070142380-A1 | Viral Polymerase Inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-21 | — | — | US | disclosed |
| US-7223785-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-29 | — | — | US | disclosed |
| EP-1630213-A1 | Ink-jet ink set and recording method using the same | Konica Minolta Medical & Graphic, Inc. (JP) | 2006-03-01 | — | — | EP | disclosed |
| US-20040227798-A1 | Ink-jet ink set and recording method using the same | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2004-11-18 | — | — | US | disclosed |
| EP-1477537-A1 | Ink-jet ink set and recording method using the same | Konica Minolta Medical & Graphic Inc. (JP) | 2004-11-17 | — | — | EP | disclosed |
| US-20030219467-A1 | Method for the inhibition of methanogensis | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2003-11-27 | — | — | US | disclosed |
| WO-2003038109-A2 | METHOD FOR THE INHIBITION OF METHANOGENESIS | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2003-05-08 | — | — | WO | disclosed |
| US-4011173-A | MODIFIED NEMATIC MIXTURES WITH POSITIVE DIELECTRIC ANISOTROPY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827640-B2 | Substituted pyrazolo[1,5-a]pyrimidines as CFTR modulators | PDE4A, PDE4B, PDE5A | HCAR3 3647/4885TDP1 264/4885TSHR 2647/4885 |
| US-10604492-B2 | CFTR regulators and methods of use thereof | CFTR, SLC26A4, CLCN2 | HCAR3 253/4885TDP1 2925/4885TSHR 610/4885 |
| US-10882883-B2 | Derivatives of amphotericin B | C9, ERG28, AMPD3 | HCAR3 1535/4885TDP1 4765/4885TSHR 3105/4885 |
| US-20070142380-A1 | Viral Polymerase Inhibitors | POLM, POLR2H, POLR2A | HCAR3 4884/4885TDP1 1197/4885TSHR 3904/4885 |
| US-20200262858-A1 | DERIVATIVES OF AMPHOTERICIN B | C9, ERG28, AMPD3 | HCAR3 1535/4885TDP1 4765/4885TSHR 3105/4885 |
| US-11198705-B2 | Hybrid Amphotericin B derivatives with reduced toxicity | ERG28, BAK1, MCL1 | HCAR3 2636/4885TDP1 3138/4885TSHR 3897/4885 |
| US-20170247340-A1 | Inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase and Uses Thereof | ACP1, PTPRCAP, PTPA | HCAR3 4350/4885TDP1 1180/4885TSHR 3240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.