Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 15/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 3/20 | 0.38 |
| ▸ | FLT4 | P35916 | 3/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19904842 | 0.82 | ALDH1A1 (0.44) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL15925187 | 0.80 | PSMD14 (0.31) | — | |
| SCHEMBL1491928 | 0.77 | MAPK9 (0.43) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL2040213 | 0.77 | ALDH1A1 (0.49) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL30450856 | 0.76 | MAPK9 (0.42) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL21647270 | 0.75 | ALDH1A1 (0.48) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL29373868 | 0.75 | ALDH1A1 (0.48) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL30125198 | 0.75 | ALDH1A1 (0.48) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL30024343 | 0.75 | ALDH1A1 (0.48) | KDRMAPK9MAPK10FLT1FLT4 | |
| SCHEMBL23884731 | 0.75 | P2RX4 (0.40) | KDRP2RX4MAPK9MAPK10FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | UNIV CALIFORNIA (US) | 2023-05-11 | — | — | US | disclosed |
| WO-2021203016-A2 | PROTEIN-PROTEIN INTERACTION STABILIZERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | HSPBP1, HSPA8, HSPH1 | KDR 4396/4885P2RX4 4803/4885MAPK9 3291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.