Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25442273 | 0.99 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2AOPRL1L3MBTL1 | |
| SCHEMBL25442296 | 0.97 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2AOPRL1L3MBTL1 | |
| SCHEMBL25442283 | 0.90 | OPRL1 (0.40) | SMN1; SMN2MEN1KMT2AOPRL1L3MBTL1 | |
| SCHEMBL25442286 | 0.89 | OPRL1 (0.41) | SMN1; SMN2OPRL1TSHRERAP1PARP1 | |
| SCHEMBL23903361 | 0.89 | NPSR1 (0.41) | SMN1; SMN2OPRL1TSHRMAPTLMNA | |
| SCHEMBL25442276 | 0.88 | ERAP1 (0.43) | SMN1; SMN2MEN1KMT2ATSHRMAPT | |
| SCHEMBL23903352 | 0.87 | ERAP1 (0.44) | SMN1; SMN2MEN1KMT2ATSHRMAPT | |
| SCHEMBL25442278 | 0.84 | GPR119 (0.50) | L3MBTL1TSHRMAPTNPC1RAB9A | |
| SCHEMBL25443137 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2AL3MBTL1ALPG | |
| SCHEMBL25442297 | 0.82 | EPHX2 (0.41) | SMN1; SMN2MAPTERAP1NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | UNIV CALIFORNIA (US) | 2023-05-11 | — | — | US | disclosed |
| WO-2021203016-A2 | PROTEIN-PROTEIN INTERACTION STABILIZERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | HSPBP1, HSPA8, HSPH1 | SMN1; SMN2 1672/4885MEN1 3934/4885KMT2A 3385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.