SCHEMBL25442286

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23903375	0.89	SMN1; SMN2 (0.44)	OPRL1OPRM1ERAP1SMN1; SMN2NPC1
	SCHEMBL25442296	0.89	SMN1; SMN2 (0.42)	OPRL1OPRM1ERAP1SMN1; SMN2NPC1
	SCHEMBL25442289	0.89	ERAP1 (0.39)	ERAP1SMN1; SMN2NPC1TP53RAB9A
	SCHEMBL25442273	0.88	SMN1; SMN2 (0.46)	OPRL1ERAP1SMN1; SMN2PARP1ALDH1A1
	SCHEMBL25442283	0.87	OPRL1 (0.40)	OPRL1OPRM1SMN1; SMN2NPC1TP53
	SCHEMBL23903361	0.86	NPSR1 (0.41)	OPRL1OPRM1SMN1; SMN2EPHX2ALDH1A1
	SCHEMBL25443176	0.82	POLB (0.37)	OPRL1OPRM1CHRM2CHRM1CHRM3
	SCHEMBL25443129	0.82	MAPT (0.35)	OPRL1OPRM1CHRM2CHRM1CHRM3
	SCHEMBL25442278	0.81	GPR119 (0.50)	NAMPTKDM4ENPC1RAB9AALDH1A1
	SCHEMBL25442297	0.80	EPHX2 (0.41)	ERAP1SMN1; SMN2NPC1TP53RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.