Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 10/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 10/20 | 0.38 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26762020 | 0.81 | ALDH1A1 (0.40) | P2RX3P2RX2HPGDSCRHR1 | |
| SCHEMBL23717026 | 0.76 | EGFR (0.38) | P2RX3P2RX2DHFRHPGDSCRHR1 | |
| SCHEMBL25113960 | 0.74 | CRHR1 (0.40) | P2RX3P2RX2CRHR1 | |
| SCHEMBL20666239 | 0.73 | DYRK1A (0.48) | — | |
| SCHEMBL23905356 | 0.73 | CA12 (0.47) | HPGDS | |
| SCHEMBL2134025 | 0.72 | HPGDS (0.60) | HPGDS | |
| SCHEMBL23717463 | 0.70 | CASR (0.34) | CRHR1 | |
| SCHEMBL2609307 | 0.70 | HPGDS (0.57) | HPGDS | |
| SCHEMBL10080963 | 0.69 | P2RX3 (0.43) | P2RX3P2RX2DHFR | |
| SCHEMBL23510806 | 0.69 | P2RX3 (0.40) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |