Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.35 |
| ▸ | SCD | O00767 | 2/20 | 0.35 |
| ▸ | OXTR | P30559 | 2/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 4/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | GPR6 | P46095 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958594 | 0.88 | CCR1 (0.44) | SYKPIK3CACCR1CCR5CCR8 | |
| SCHEMBL23905332 | 0.83 | SYK (0.37) | SYKPIK3CACCR1CCR5CCR8 | |
| SCHEMBL23904831 | 0.79 | CA12 (0.38) | PDGFRBPDGFRA | |
| SCHEMBL23904835 | 0.78 | SCD (0.39) | SCD | |
| SCHEMBL23905484 | 0.77 | CCR1 (0.40) | SYKPIK3CACCR1CCR5CCR8 | |
| SCHEMBL23905312 | 0.75 | MCHR1 (0.39) | SYKSCDCCR1CCR5CCR8 | |
| SCHEMBL23905370 | 0.73 | ELANE (0.37) | CCR1CCR5CCR8 | |
| SCHEMBL20064280 | 0.72 | MCHR1 (0.48) | GRM5 | |
| SCHEMBL23196004 | 0.72 | KMO (0.40) | CCR1CCR5CCR8 | |
| SCHEMBL30007139 | 0.72 | KMO (0.40) | CCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |