Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 6/20 | 0.38 |
| ▸ | SCD | O00767 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23195900 | 0.85 | KMO (0.44) | KMT2AKMOHCAR2PDE4DPDE4A | |
| SCHEMBL23904848 | 0.85 | KMO (0.37) | KMT2AKMOSCDPDE4DPDE4A | |
| SCHEMBL23904835 | 0.84 | SCD (0.39) | KMT2AKMOSCDHCAR2PDE4D | |
| SCHEMBL30007139 | 0.84 | KMO (0.40) | KMT2AKMOHCAR2PDE4DPDE4A | |
| SCHEMBL23196004 | 0.84 | KMO (0.40) | KMT2AKMOHCAR2PDE4DPDE4A | |
| SCHEMBL23905324 | 0.84 | OPRK1 (0.42) | OPRK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23904830 | 0.82 | KMT2A (0.44) | KMT2AKMOPDE4DPDE4APDE4B | |
| SCHEMBL23195609 | 0.81 | CA12 (0.47) | KMT2APOLBHCAR2 | |
| SCHEMBL23195592 | 0.77 | LMNA (0.44) | KMOPDE4DPDE4A | |
| SCHEMBL29620722 | 0.77 | LMNA (0.44) | KMOPDE4DPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |