Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | CCR1 | P32246 | 2/20 | 0.48 |
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
| ▸ | CCR8 | P51685 | 2/20 | 0.48 |
| ▸ | PRNP | P04156 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.40 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23928044 | 0.84 | KDM4E (0.63) | KDM4ECCR1CCR5CCR8PRNP | |
| SCHEMBL28643220 | 0.82 | KDM4E (0.61) | KDM4ECCR1CCR5CCR8PRNP | |
| SCHEMBL20176008 | 0.78 | LMNA (0.40) | KDM4EPRNPNPSR1LMNAHPGD | |
| SCHEMBL30748621 | 0.78 | CCR1 (0.48) | KDM4ECCR1CCR5CCR8PRNP | |
| SCHEMBL28453161 | 0.78 | HTT (0.40) | KDM4EPRNPNPSR1LMNAHPGD | |
| SCHEMBL23905909 | 0.75 | ALDH1A1 (0.50) | KDM4ECCR1CCR5CCR8PRNP | |
| SCHEMBL12725651 | 0.74 | PRNP (0.43) | KDM4EPRNPNPSR1LMNAHPGD | |
| SCHEMBL23195914 | 0.74 | KDM4E (0.51) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL31654043 | 0.74 | PSMD14 (0.45) | KDM4EPRNPNPSR1LMNAHPGD | |
| SCHEMBL1787225 | 0.72 | KDM4E (1.00) | KDM4ECCR1CCR5CCR8PSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |