Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.42 |
| ▸ | PDE4A | P27815 | 5/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905519 | 0.84 | HSD17B2 (0.42) | PDE4DPDE4APDE4BPDE4CMAPT | |
| SCHEMBL23904830 | 0.84 | KMT2A (0.44) | HPGDSPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL23958784 | 0.76 | PDE4A (0.39) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL23905722 | 0.74 | HPGDS (0.45) | HPGDSPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL25687961 | 0.72 | ATM (0.41) | HPGDSPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL23905483 | 0.71 | CA12 (0.39) | PDE4DPDE4BSMN1; SMN2MAPTRAB9A | |
| SCHEMBL23883070 | 0.71 | KDM4E (0.46) | HPGDSMAPTKDM4EALDH1A1 | |
| SCHEMBL23905310 | 0.70 | CA12 (0.38) | RAB9A | |
| SCHEMBL23904867 | 0.69 | MEN1 (0.48) | HPGDSSMN1; SMN2MAPTRAB9AL3MBTL1 | |
| SCHEMBL23196004 | 0.69 | KMO (0.40) | PDE4DPDE4APDE4BPDE4CDGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |