Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | STAMBP | O95630 | 1/20 | 0.38 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23195900 | 0.85 | KMO (0.44) | IP6K1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23905310 | 0.82 | CA12 (0.38) | — | |
| SCHEMBL23905397 | 0.81 | HPGDS (0.51) | HPGDSHPGDKAT2BBAZ2BPSMD14 | |
| SCHEMBL25687961 | 0.74 | ATM (0.41) | HPGDSALDH1A1PSMD14PDE4APDE4B | |
| SCHEMBL23958784 | 0.74 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23905586 | 0.74 | HPGDS (0.47) | HPGDSALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL23196004 | 0.73 | KMO (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30007139 | 0.73 | KMO (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30211305 | 0.72 | PARP1 (0.43) | PSMD14STAMBPCOPS5PDE4APDE4B | |
| SCHEMBL23904830 | 0.72 | KMT2A (0.44) | HPGDSPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |