Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | MTTP | P55157 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905655 | 0.93 | ADRA1D (0.31) | MAPTROCK2ROCK1MTTPADRA1D | |
| SCHEMBL23905665 | 0.90 | MAPT (0.33) | MAPTROCK2ROCK1 | |
| SCHEMBL23905959 | 0.90 | MAPT (0.34) | MAPTROCK2ROCK1ADRA1DADRA1A | |
| SCHEMBL23904705 | 0.87 | — | — | |
| SCHEMBL23905824 | 0.85 | — | — | |
| SCHEMBL23905991 | 0.84 | ROCK2 (0.32) | MAPTROCK2ROCK1MTTP | |
| SCHEMBL23905980 | 0.84 | ADRA1D (0.33) | MAPTROCK2ROCK1MTTPADRA1D | |
| SCHEMBL23905652 | 0.83 | ADRA1D (0.34) | MAPTADRA1DADRA1AADRA1B | |
| SCHEMBL23905664 | 0.83 | MAPT (0.33) | MAPTROCK2ROCK1 | |
| SCHEMBL23905254 | 0.82 | POLB (0.32) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |