Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | MTTP | P55157 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904897 | 0.95 | — | — | |
| SCHEMBL23905652 | 0.94 | ADRA1D (0.34) | ADRA1DADRA1AADRA1BMAPTSMN1; SMN2 | |
| SCHEMBL23904706 | 0.88 | — | — | |
| SCHEMBL23905804 | 0.87 | ADRA1D (0.32) | ADRA1DADRA1AADRA1B | |
| SCHEMBL23905976 | 0.84 | MAPT (0.32) | ADRA1DADRA1AADRA1BMAPTROCK2 | |
| SCHEMBL23905655 | 0.83 | ADRA1D (0.31) | ADRA1DADRA1AADRA1BMAPTROCK2 | |
| SCHEMBL23905642 | 0.83 | POLB (0.30) | MAPT | |
| SCHEMBL23958775 | 0.83 | ADRA1D (0.36) | ADRA1DADRA1AADRA1BMAPTSMN1; SMN2 | |
| SCHEMBL23905797 | 0.81 | PTGFR (0.32) | MAPTSMN1; SMN2 | |
| SCHEMBL23905949 | 0.81 | PTGFR (0.31) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |