Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALKBH2 | Q6NS38 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23907175 | 1.00 | KMT2A (0.45) | KMT2ACA12CA9L3MBTL1MEN1 | |
| SCHEMBL22216353 | 0.86 | POLB (0.51) | KMT2AMEN1NPSR1ALDH1A1KDM4E | |
| SCHEMBL29441565 | 0.86 | POLB (0.51) | KMT2AMEN1NPSR1ALDH1A1KDM4E | |
| SCHEMBL23920594 | 0.81 | ALDH1A1 (0.51) | KMT2AL3MBTL1MEN1NPSR1ALDH1A1 | |
| SCHEMBL23907151 | 0.78 | CA12 (0.47) | KMT2ACA12CA9MEN1GSK3B | |
| SCHEMBL23907155 | 0.78 | CA12 (0.47) | KMT2ACA12CA9MEN1GSK3B | |
| SCHEMBL23907325 | 0.78 | CA12 (0.47) | KMT2ACA12CA9MEN1GSK3B | |
| SCHEMBL23907322 | 0.78 | CA12 (0.47) | KMT2ACA12CA9MEN1GSK3B | |
| SCHEMBL23907233 | 0.77 | L3MBTL1 (0.49) | L3MBTL1ALKBH2HPGDSEGLN1 | |
| SCHEMBL23907231 | 0.77 | L3MBTL1 (0.49) | L3MBTL1ALKBH2HPGDSEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892621-A1 | HALOALLYLAMINE COMPOUNDS AND APPLICATION THEREOF | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |