SCHEMBL23907287

SCHEMBL23907287

CCNC(=O)c1cnn(C/C(=C/F)CNC(=O)O)c1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.39
HPGD P15428 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
KLKB1 P03952 11/20 0.37
CYP2C19 P33261 2/20 0.36
MAPT P10636 2/20 0.36
GFER P55789 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
HTT P42858 1/20 0.35
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
RECQL P46063 1/20 0.34
PDK2 Q15119 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23907289 1.00 LMNA (0.39) LMNAHPGDL3MBTL1KLKB1CYP2C19
SCHEMBL22207006 0.89 L3MBTL1 (0.36) LMNAHPGDL3MBTL1KLKB1CYP2C19
SCHEMBL22207003 0.89 L3MBTL1 (0.36) LMNAHPGDL3MBTL1KLKB1CYP2C19
SCHEMBL22216455 0.88 LMNA (0.42) LMNAHPGDL3MBTL1KLKB1CYP2C19
SCHEMBL23907203 0.86 AOC3 (0.38) LMNAHPGDL3MBTL1KLKB1CYP2C19
SCHEMBL23907200 0.86 AOC3 (0.38) LMNAHPGDL3MBTL1KLKB1CYP2C19
SCHEMBL22216339 0.85 KLKB1 (0.41) LMNAHPGDL3MBTL1KLKB1CYP2C19
SCHEMBL22207026 0.85 LMNA (0.35) LMNAHPGDL3MBTL1KLKB1CYP2C19
SCHEMBL22207024 0.85 LMNA (0.35) LMNAHPGDL3MBTL1KLKB1CYP2C19
SCHEMBL23907208 0.83 MAPK11 (0.40) HPGDKLKB1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3892621-A1 HALOALLYLAMINE COMPOUNDS AND APPLICATION THEREOF Nanjing Transthera Biosciences Co., Ltd. (CN) 2021-10-13 EP disclosed