SCHEMBL23907200

SCHEMBL23907200

CC(C)(C)NC(=O)c1cnn(C/C(=C/F)CNC(=O)O)c1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 4/20 0.38
MAOB P27338 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.34
KLKB1 P03952 8/20 0.34
LMNA P02545 3/20 0.33
ACHE P22303 2/20 0.33
HPGD P15428 1/20 0.33
MAPT P10636 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP2C19 P33261 1/20 0.32
GFER P55789 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23907203 1.00 AOC3 (0.38) AOC3MAOBL3MBTL1KLKB1LMNA
SCHEMBL22216189 0.88 AOC3 (0.40) AOC3MAOBL3MBTL1KLKB1LMNA
SCHEMBL22207003 0.87 L3MBTL1 (0.36) L3MBTL1KLKB1LMNAACHEHPGD
SCHEMBL22207006 0.87 L3MBTL1 (0.36) L3MBTL1KLKB1LMNAACHEHPGD
SCHEMBL29441559 0.87 AOC3 (0.38) AOC3MAOBKLKB1LMNAACHE
SCHEMBL28435846 0.87 AOC3 (0.38) AOC3MAOBKLKB1LMNAACHE
SCHEMBL22216190 0.87 AOC3 (0.42) AOC3MAOBL3MBTL1LMNAACHE
SCHEMBL23907289 0.86 LMNA (0.39) L3MBTL1KLKB1LMNAHPGDMAPT
SCHEMBL23907287 0.86 LMNA (0.39) L3MBTL1KLKB1LMNAHPGDMAPT
SCHEMBL22216397 0.85 AOC3 (0.51) AOC3MAOBL3MBTL1KLKB1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3892621-A1 HALOALLYLAMINE COMPOUNDS AND APPLICATION THEREOF Nanjing Transthera Biosciences Co., Ltd. (CN) 2021-10-13 EP disclosed