Sugi Predict

Sugi Predict / Compounds / SCHEMBL23908284

SCHEMBL23908284

SCHEMBL23908284

CC(C)(C)c1ccc(Nc2cccc(Nc3ccc(-c4ccccc4)cc3)c2Cl)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 1/20 0.46
▸ ABCG2 Q9UNQ0 1/20 0.45
▸ SERPINE1 P05121 1/20 0.41
▸ KIF11 P52732 2/20 0.41
▸ NPC1 O15118 2/20 0.40
▸ RAB9A P51151 2/20 0.40
▸ GLA P06280 2/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ ATM Q13315 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ AKR1C3 P42330 3/20 0.40
▸ HSD17B2 P37059 1/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ MAPT P10636 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ LMNA P02545 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ AKR1C2 P52895 2/20 0.39
▸ CCR4 P51679 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24178525 0.90 RAB9A (0.42) CNR1ABCG2KIF11NPC1RAB9A
SCHEMBL25106540 0.89 CNR1 (0.42) CNR1ABCG2KIF11NPC1RAB9A
SCHEMBL22819597 0.88 ABCG2 (0.45) CNR1ABCG2SERPINE1KIF11NPC1
SCHEMBL20209149 0.83 ABCG2 (0.54) CNR1ABCG2SERPINE1KIF11ALDH1A1
SCHEMBL22080286 0.83 ABCG2 (0.54) CNR1ABCG2SERPINE1KIF11ALDH1A1
SCHEMBL605442 0.83 ABCG2 (0.54) CNR1ABCG2SERPINE1KIF11ALDH1A1
SCHEMBL25705736 0.82 RAB9A (0.46) NPC1RAB9AGLAALDH1A1ATM
SCHEMBL24948445 0.81 RAB9A (0.39) CNR1NPC1RAB9AGLAALDH1A1
SCHEMBL25705778 0.81 ABCG2 (0.42) CNR1ABCG2SERPINE1KIF11NPC1
SCHEMBL12357213 0.80 CNR1 (0.50) CNR1ABCG2SERPINE1KIF11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11845768-B2 Polycyclic compound and organic light-emitting device including same LG CHEM, LTD. (KR) 2023-12-19 — — US disclosed
CN-112585145-B Polycyclic compound and organic light emitting device including the same 株式会社LG化学 2023-09-29 — — CN disclosed
CN-113853694-B organic light emitting device 株式会社LG化学 2023-09-05 — — CN disclosed
US-20230090371-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-03-23 — — US disclosed
CN-113853694-A Organic light emitting device 株式会社LG化学 2021-12-28 — — CN disclosed
US-20210317147-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME LG CHEM, LTD. (KR) 2021-10-14 — — US disclosed
US-20210317147-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME LG CHEM, LTD. (KR) 2021-10-14 — — US disclosed
CN-112585145-A Polycyclic compound and organic light emitting device including the same 株式会社LG化学 2021-03-30 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317147-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME CYP1A1, CRY1, CYP1B1 CNR1 941/4885ABCG2 3013/4885SERPINE1 3654/4885
US-11845768-B2 Polycyclic compound and organic light-emitting device including same CRY1, CYP1A1, CRY2 CNR1 1130/4885ABCG2 1535/4885SERPINE1 4087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.