SCHEMBL22080286

SCHEMBL22080286

CC(C)(C)c1ccc(-c2ccc(Nc3ccc(-c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.54
KIF11 P52732 5/20 0.50
HSD17B10 Q99714 2/20 0.48
ALDH1A1 P00352 1/20 0.48
ALOX15 P16050 1/20 0.48
TSHR P16473 1/20 0.48
ALOX12 P18054 1/20 0.48
PTGS1 P23219 1/20 0.48
SLC6A2 P23975 1/20 0.48
MAPK1 P28482 1/20 0.48
PTGS2 P35354 1/20 0.48
HTR2B P41595 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
SERPINE1 P05121 1/20 0.47
HPGD P15428 1/20 0.45
CNR1 P21554 1/20 0.44
CYP19A1 P11511 2/20 0.43
HSD17B2 P37059 1/20 0.43
XDH P47989 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL605442 1.00 ABCG2 (0.54) ABCG2KIF11HSD17B10ALDH1A1ALOX15
SCHEMBL20209149 1.00 ABCG2 (0.54) ABCG2KIF11HSD17B10ALDH1A1ALOX15
SCHEMBL12367613 0.96 ALDH1A1 (0.54) ABCG2KIF11HSD17B10ALDH1A1ALOX15
SCHEMBL13133429 0.96 ALDH1A1 (0.54) ABCG2KIF11HSD17B10ALDH1A1ALOX15
SCHEMBL12357213 0.93 CNR1 (0.50) ABCG2KIF11ALDH1A1SERPINE1CNR1
SCHEMBL13321302 0.91 KIF11 (0.57) ABCG2KIF11TSHRMAPK1XDH
SCHEMBL2957181 0.91 KIF11 (0.57) ABCG2KIF11TSHRMAPK1XDH
SCHEMBL24732147 0.89 CNR1 (0.55) ABCG2KIF11HSD17B10ALDH1A1ALOX15
SCHEMBL502030 0.89 ALDH1A1 (0.62) ABCG2HSD17B10ALDH1A1ALOX15TSHR
Diphenylamine SCHEMBL29287150 0.89 ALDH1A1 (0.62) ABCG2HSD17B10ALDH1A1ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024096383-A1 ORGANIC ELECTRONIC DEVICE COMPRISING PLURALITY OF LIGHT-EMITTING AUXILIARY LAYERS, AND ELECTRONIC APPARATUS THEREFOR 덕산네오룩스 주식회사 2024-05-10 WO disclosed
US-11618757-B2 Polycyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2023-04-04 US disclosed
US-20200181165-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2020-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200181165-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, PER2 ABCG2 1994/4885KIF11 2798/4885HSD17B10 2086/4885
US-11618757-B2 Polycyclic compound and organic light emitting element comprising same CRY1, CRY2, PER2 ABCG2 1994/4885KIF11 2798/4885HSD17B10 2086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.