SCHEMBL2390868

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2390747	0.91	ROCK2 (0.62)	NAMPTROCK2SPRPROKR1NPC1
	SCHEMBL2390964	0.89	NAMPT (0.53)	NAMPTROCK2SPRPROKR1EPHX2
	SCHEMBL2388732	0.89	NAMPT (0.52)	NAMPTROCK2SPRPROKR1CYP2C9
	SCHEMBL2389753	0.89	NAMPT (0.52)	NAMPTROCK2SPRPROKR1CYP2C9
	SCHEMBL2389098	0.89	NAMPT (0.56)	NAMPTROCK2SPRPROKR1CYP2C9
	SCHEMBL2390814	0.89	NAMPT (0.56)	NAMPTROCK2SPRPROKR1CYP2C9
	SCHEMBL2390754	0.89	NAMPT (0.56)	NAMPTROCK2SPRPROKR1CYP2C9
	SCHEMBL2389357	0.89	NAMPT (0.59)	NAMPTROCK2SPRPROKR1CYP2C9
	SCHEMBL2391739	0.88	NAMPT (0.56)	NAMPTROCK2SPRPROKR1CYP2C9
	SCHEMBL2387224	0.88	NAMPT (0.56)	NAMPTROCK2SPRPROKR1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.